GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-

CAS 139504-68-0

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- (CAS 139504-68-0) is a chemical substance; key hazard signal: H411. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 2-T-Butylcyclohexyloxybutanol →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields

Name

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-

CAS Number

139504-68-0

DTXSID

DTXSID00869896

Molecular Formula

C14H28O2

InChI Key

GQBVHGLNSHPKPG-UHFFFAOYSA-N

Monoisotopic Mass

228.20893

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Aquatic Chronic 2	H411	GHS09	-

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 38 records

DeodorizerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records

List	Keyword	Source
IFRA Transparency	IFRA	IFRA
consumer_product	P&G	Proctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 9 of 9 studies

Value	Unit	Endpoint	Route	Species	Source
=17.6	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
1DR20642YH	UNII	FDA UNII substance identifier	-	-	openFDA substances
1DR20642YH	UNII	FDA UNII substance identifier	-	-	openFDA substances
1DR20642YH	UNII	FDA UNII substance identifier	-	-	openFDA substances
1DR20642YH	UNII	FDA UNII substance identifier	-	-	openFDA substances
~1000	mg/kg bw/day	LOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
~140	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
~500	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_ECHA_IUCLID
=20	mg/kg bw/day	NOEL	oral	Rat	ToxValDB_ECHA_IUCLID

Showing 9 of 9 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol	412-300-2	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed_with_terms

Conditions

Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3733013

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-?

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- (CAS 139504-68-0) is classified under EU CLP Annex VI as Aquatic Chronic 2. Hazard statements: H411. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-?

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- has 9 NOAEL studies in the database. The lowest reported value is 17.6 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-?

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.

Is 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- used in cosmetics?

Yes, 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- is also indexed as a cosmetic ingredient under the name 2-T-Butylcyclohexyloxybutanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- used outside industrial chemicals?

2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]- also appears in cosmetics, pharmaceutical databases.