What is the NOAEL for Linalool oxide?
Linalool oxide has 7 NOAEL studies in the database. The lowest reported value is 4UJJ55KMCS UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Linalool oxide
Also known as: EINECS 215-723-9, FEMA No. 3746, Linalool, epoxydihydro-, Linalool, oxide, UNII-4UJJ55KMCS
CAS 1365-19-1
Linalool oxide (CAS 1365-19-1) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Linalool oxide is classified GHS Danger (H302, H314, H315, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Linalool oxide
CAS Number
1365-19-1
DTXSID
DTXSID6052746
Molecular Formula
C10H18O2
InChI Key
BXOURKNXQXLKRK-ZJUUUORDSA-N
Monoisotopic Mass
170.13068
Synonyms
EINECS 215-723-9FEMA No. 3746Linalool, epoxydihydro-Linalool, oxideUNII-4UJJ55KMCS
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
14 records
FragranceNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4UJJ55KMCS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4UJJ55KMCS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4UJJ55KMCS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4UJJ55KMCS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 5400 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Linalool oxide?
Linalool oxide appears on 4 regulatory/inventory lists including Australia; Food and drug - smoking-related products, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Linalool oxide used in cosmetics?
Yes, Linalool oxide is also indexed as a cosmetic ingredient under the name Linalool Oxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Linalool oxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Linalool oxide have different safety status in cosmetics vs industrial chemicals?
Linalool oxide is classified GHS Danger (H302, H314, H315, H319) in the chemicals database but is allowed in EU cosmetics.
Is Linalool oxide used outside industrial chemicals?
Linalool oxide also appears in cosmetics, cannabis databases.