What is the NOAEL for Zirconium dioxide?
Zirconium dioxide has 4 NOAEL studies in the database. The lowest reported value is S38N85C5G0 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Zirconium dioxide
Also known as: Zirconium oxide (ZrO2), EINECS 215-227-2, Rhuligel, UNII-S38N85C5G0
CAS 1314-23-4
Zirconium dioxide (CAS 1314-23-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Zirconium dioxide
CAS Number
1314-23-4
DTXSID
DTXSID1042520
Molecular Formula
O2Zr
InChI Key
RVTZCBVAJQQJTK-UHFFFAOYSA-N
Monoisotopic Mass
121.89453
Synonyms
Zirconium oxide (ZrO2)EINECS 215-227-2RhuligelUNII-S38N85C5G0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
27 records
OpaciferPigmentDegradant/impurityFillerSurface modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| S38N85C5G0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S38N85C5G0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S38N85C5G0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S38N85C5G0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Zirconium dioxide | 215-227-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Frequently Asked Questions
What regulatory lists include Zirconium dioxide?
Zirconium dioxide appears on 2 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Zirconium dioxide used in cosmetics?
Yes, Zirconium dioxide is also indexed as a cosmetic ingredient under the name ZIRCONIUM DIOXIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Zirconium dioxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Zirconium dioxide used outside industrial chemicals?
Zirconium dioxide also appears in cosmetics databases.