What is the NOAEL for Magnesium oxide?
Magnesium oxide has 5 NOAEL studies in the database. The lowest reported value is 3A3U0GI71G UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Magnesium oxide
Also known as: Magnesium oxide (MgO), Akro-mag, Calcined brucite, EINECS 215-171-9, Granmag (+15 more)
CAS 1309-48-4
Magnesium oxide (CAS 1309-48-4) is a chemical substance. Key regulatory status: 11 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC, OSHA.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
11
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Magnesium oxide
CAS Number
1309-48-4
DTXSID
DTXSID9049665
Molecular Formula
Mg.O
InChI Key
AXZKOIWUVFPNLO-UHFFFAOYSA-N
Monoisotopic Mass
39.979956
Synonyms
Magnesium oxide (MgO)Akro-magCalcined bruciteEINECS 215-171-9GranmagHeavy calcined magnesiaHeavy magnesiaHeavy magnesium oxideLight magnesiaMagchem 100Magnesia monoxideMagox OP
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Hazard Statements | No hazard classification according to GHS criteria |
| Short-term Effects | May cause mechanical irritation. |
| Long-term Effects | Lungs may be affected by repeated or prolongated exposure to dust particles. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of dust or fume. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
4 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 15 mg/m³ (total particulate) | - | 15 | N |
| ACGIH | TWA | 10 mg/m³ (inhalable particulate matter) [2000] | - | 10 | N |
| CAL/OSHA | TWA | 10 mg/m³ | - | 10 | N |
| NIOSH | IDLH | 750 mg/m³ | - | 750 | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
AbsorbentpH regulating agentOpaciferBinderFlux agentFlame retardantNo specific technical functionDegradant/impurityFillerCatalyst
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
11 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| fracking | FracFocus | FracFocus |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 3A3U0GI71G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3A3U0GI71G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3A3U0GI71G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3A3U0GI71G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 250 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MAGNESIUM OXIDE
ChEMBL Phase
4
Adverse Events
6099
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E530 — ADI: NOT LIMITED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Magnesium oxide?
Magnesium oxide appears on 10 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 7 more. Source: EPA CPDat.
What are the occupational exposure limits for Magnesium oxide?
Occupational exposure limits for Magnesium oxide are set by OSHA, ACGIH, CAL/OSHA. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Magnesium oxide used in cosmetics?
Yes, Magnesium oxide is also indexed as a cosmetic ingredient under the name Magnesium Oxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Magnesium oxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Magnesium oxide used outside industrial chemicals?
Magnesium oxide also appears in cosmetics, pharmaceutical, food safety, cannabis databases.