NOAEL Data REACH Registered Cosmetic Ingredient

Calcium hydroxide

Also known as: Ca(OH)2, Calcium hydroxide (Ca(OH)2), Bell mine, Caswell No. 144, EINECS 215-137-3 (+6 more)

CAS 1305-62-0

Calcium hydroxide (CAS 1305-62-0) is a chemical substance. Key regulatory status: REACH registered, 25 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA.

View cosmetic safety profile for Calcium Hydroxide →

Cross-Vertical Regulatory Divergence

Calcium hydroxide is classified GHS Danger (H314, H315, H318, H335, H370, H373) in the chemicals database but is restricted in EU cosmetics at max 7%.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 17 fields

Name

Calcium hydroxide

CAS Number

1305-62-0

DTXSID

DTXSID7034410

Molecular Formula

Ca.2H2O

InChI Key

AXCZMVOFGPJBDE-UHFFFAOYSA-L

Monoisotopic Mass

75.98372

Synonyms

Ca(OH)2Calcium hydroxide (Ca(OH)2)Bell mineCaswell No. 144EINECS 215-137-3EPA Pesticide Chemical Code 075601KemikalUNII-PF5DZW74VNKalziumhydroxidLoeschkalkgeloeschter Kalk

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
Short-term Effects	The substance is corrosive to the eyes and skin. The substance is irritating to the respiratory tract. Medical observation is indicated.
Long-term Effects	Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation of dust particles may cause effects on the lungs.
Routes of Exposure	The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

OSHA Exposure Limits

Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.

SOURCE OSHA / NIOSH / ACGIH occupational exposure limits 3 records

Agency	Metric	Value	ppm	mg/m3	Skin
OSHA	TWA	15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)	-	15	N
NIOSH	TWA	5 mg/m³	-	5	N
CAL/OSHA	TWA	5 mg/m³	-	5	N

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records

pH regulating agentFlame retardantFillerBinderCatalystChemical reaction regulatorFlocculating agentProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 25 records

List	Keyword	Source
Europe; plastic_additive	European Chemicals Agency	European Chemicals Agency (ECHA)
active_ingredient; Europe; Pesticides	Commission of the European Communities	CPCat
drinking_water; Europe; manufacturing; plastic_additive	Belgaqua	CPCat
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
active_ingredient; Europe; Pesticides	European Commission	CPCat
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
active_ingredient; animal_products; Europe; pharmaceutical; residue	EU	CPCat
Europe; supplements	EU	CPCat
Europe; food_additive; supplements	EU	CPCat
Europe; Personal care; restricted	European Commission	CosIng
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)
SCIL (9/2019)	USEPA	Safer Chemical Ingredients List

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies

Value	Unit	Endpoint	Route	Species	Source
=1	mg/m3	DNEL local	inhalation	Human	ToxValDB_GESTIS_DNEL
PF5DZW74VN	UNII	FDA UNII substance identifier	-	-	openFDA substances
PF5DZW74VN	UNII	FDA UNII substance identifier	-	-	openFDA substances
PF5DZW74VN	UNII	FDA UNII substance identifier	-	-	openFDA substances
PF5DZW74VN	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Calcium dihydroxide	215-137-3	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CALCIUM HYDROXIDE

ChEMBL Phase

Adverse Events

Bioactivity

View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E526 — ADI: NOT LIMITED mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Calcium hydroxide?

Calcium hydroxide has 5 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Calcium hydroxide?

Calcium hydroxide appears on 12 regulatory/inventory lists including Europe; plastic_additive, active_ingredient; Europe; Pesticides, drinking_water; Europe; manufacturing; plastic_additive, and 9 more. Source: EPA CPDat.

What are the occupational exposure limits for Calcium hydroxide?

Occupational exposure limits for Calcium hydroxide are set by OSHA, NIOSH, CAL/OSHA. 3 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.

Is Calcium hydroxide used in cosmetics?

Yes, Calcium hydroxide is also indexed as a cosmetic ingredient under the name Calcium Hydroxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Calcium hydroxide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Does Calcium hydroxide have different safety status in cosmetics vs industrial chemicals?

Calcium hydroxide is classified GHS Danger (H314, H315, H318, H335, H370, H373) in the chemicals database but is restricted in EU cosmetics at max 7%.

Is Calcium hydroxide used outside industrial chemicals?

Calcium hydroxide also appears in cosmetics, pharmaceutical, food safety, cannabis databases.