NOAEL Data Cosmetic Ingredient

Bentonite

Also known as: Albagel Premium USP 4444, Bentonite 2073, Bentonite magma, Colloidal clay, EINECS 215-108-5 (+12 more)

CAS 1302-78-9

Bentonite (CAS 1302-78-9) is a chemical substance. Key regulatory status: 24 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.

View cosmetic safety profile for Bentonite →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 20 fields

Name

Bentonite

CAS Number

1302-78-9

DTXSID

DTXSID6030782

Synonyms

Albagel Premium USP 4444Bentonite 2073Bentonite magmaColloidal clayEINECS 215-108-5Imvite I.G.B.AMagbondPanther creek bentoniteSouthern bentoniteTixotonVolcaly bentonite BCAquagel

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
GHS Signal Word	DANGER
GHS Hazard Statements	Causes damage to the lungs through prolonged or repeated exposure if inhaled
Short-term Effects	The substance is mildly irritating to the eyes and skin.
Long-term Effects	The substance may have effects on the lungs. This may result in fibrosis (see ICSC 0808).
Routes of Exposure	The substance can be absorbed into the body by inhalation.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records

DefoamerAbsorbentViscosity modifierEmulsifierFillerSoftener and conditionerStabilizing agentThickening agentOpaciferDispersing agentSealant (barrier)

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 24 records

List	Keyword	Source
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
active_ingredient; Europe; Pesticides	Commission of the European Communities	CPCat
Europe; Personal care - hair styling and care - shampoo-dandruff	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair styling and care - shampoo-dandruff	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - hair styling and care - shampoo-dandruff	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
IFRA Transparency	IFRA	IFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)
SCIL (9/2019)	USEPA	Safer Chemical Ingredients List
Canada; pharmaceutical	DrugBank	DrugBank
Cleaning products and household care - laundry and fabric treatment - laundry detergent; Europe	Danish EPA	Danish EPA
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe	Danish EPA	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies

Value	Unit	Endpoint	Route	Species	Source
A3N5ZCN45C	UNII	FDA UNII substance identifier	-	-	openFDA substances
A3N5ZCN45C	UNII	FDA UNII substance identifier	-	-	openFDA substances
A3N5ZCN45C	UNII	FDA UNII substance identifier	-	-	openFDA substances
A3N5ZCN45C	UNII	FDA UNII substance identifier	-	-	openFDA substances
400	mg/kg bw/day	NOAEL	oral	rat	COSMOS_DB
1000	mg/kg bw/day	NOAEL	oral	rat	COSMOS_DB
75000	mg/kg bw/day	NOAEL	oral	mouse	COSMOS_DB

Showing 7 of 7 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Bentonite?

Bentonite has 7 NOAEL studies in the database. The lowest reported value is A3N5ZCN45C UNII. Source: openFDA substances.

What regulatory lists include Bentonite?

Bentonite appears on 12 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 9 more. Source: EPA CPDat.

Is Bentonite used in cosmetics?

Yes, Bentonite is also indexed as a cosmetic ingredient under the name Bentonite. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bentonite come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Bentonite used outside industrial chemicals?

Bentonite also appears in cosmetics, cannabis databases.