What is the NOAEL for 2-O-Hexopyranosylhex-1-enofuranos-3-ulose?
2-O-Hexopyranosylhex-1-enofuranos-3-ulose has 4 NOAEL studies in the database. The lowest reported value is 2V52R0NHXW UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-O-Hexopyranosylhex-1-enofuranos-3-ulose
Also known as: 2-O-α-D-Glucopyranosyl-L-ascorbic acid, (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,5-dihydrofuran-2-one, AA 2G, Ascofresh, EC 425-980-0
CAS 129499-78-1
2-O-Hexopyranosylhex-1-enofuranos-3-ulose (CAS 129499-78-1) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
2-O-Hexopyranosylhex-1-enofuranos-3-ulose
CAS Number
129499-78-1
DTXSID
DTXSID50926423
Molecular Formula
C12H18O11
InChI Key
YEERNPPBIMJBHH-DCWMUDTNSA-N
Monoisotopic Mass
338.084911
Synonyms
2-O-α-D-Glucopyranosyl-L-ascorbic acid(5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,5-dihydrofuran-2-oneAA 2GAscofreshEC 425-980-0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Antioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2V52R0NHXW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2V52R0NHXW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2V52R0NHXW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2V52R0NHXW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,5-dihydrofuran-2-one | 425-980-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL2011961
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include 2-O-Hexopyranosylhex-1-enofuranos-3-ulose?
2-O-Hexopyranosylhex-1-enofuranos-3-ulose appears on 2 regulatory/inventory lists including Canada; pharmaceutical, Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is 2-O-Hexopyranosylhex-1-enofuranos-3-ulose used in cosmetics?
Yes, 2-O-Hexopyranosylhex-1-enofuranos-3-ulose is also indexed as a cosmetic ingredient under the name Ascorbyl Glucoside. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-O-Hexopyranosylhex-1-enofuranos-3-ulose come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-O-Hexopyranosylhex-1-enofuranos-3-ulose used outside industrial chemicals?
2-O-Hexopyranosylhex-1-enofuranos-3-ulose also appears in cosmetics, pharmaceutical databases.