Also known as: 2-Amino-2-methyl-1-propanol, beta-Aminoisobutanol, BRN 0505979, Caswell No. 037, EINECS 204-709-8 (+3 more)
CAS 124-68-5
2-Amino-2-methylpropan-1-ol (CAS 124-68-5) is a chemical substance with GHS signal word Warning; key hazard signal: H315; H319; H412. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Skin Irrit. 2; Eye Irrit. 2; Aquatic Chronic 3 | H315; H319; H412 | GHS07 | Warning |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The substance is corrosive to the eyes. The substance is severely irritating to the skin. The aerosol is irritating to the respiratory tract. |
| Long-term Effects | Ingestion may cause effects on the liver. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts adhesive; Europe | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts paint; Europe | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =6.5 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| LU49E6626Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LU49E6626Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LU49E6626Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| LU49E6626Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =240 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_HPVIS |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 7 of 7 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-amino-2-methylpropanol | 204-709-8 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
2-Amino-2-methylpropan-1-ol (CAS 124-68-5) is classified under EU CLP Annex VI as Skin Irrit. 2; Eye Irrit. 2; Aquatic Chronic 3 with signal word Warning. Hazard statements: H315; H319; H412. Source: EU CLP Annex VI (ECHA).
2-Amino-2-methylpropan-1-ol has 7 NOAEL studies in the database. The lowest reported value is 6.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
2-Amino-2-methylpropan-1-ol appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Indirect additives food contact (10/2018), Arts and crafts/Office supplies - general arts and crafts supplies - arts and crafts adhesive; Europe, and 2 more. Source: EPA CPDat.
Yes, 2-Amino-2-methylpropan-1-ol is also indexed as a cosmetic ingredient under the name Aminomethyl Pro. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
2-Amino-2-methylpropan-1-ol also appears in cosmetics, pharmaceutical databases.