What is the NOAEL for Carbon dioxide?
Carbon dioxide has 4 NOAEL studies in the database. The lowest reported value is 142M471B3J UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Carbon dioxide
Also known as: CO2, AER Fixus, After-damp, Carbon oxide, di-, Carbonica (+14 more)
CAS 124-38-9
Carbon dioxide (CAS 124-38-9) is a chemical substance. Key regulatory status: 25 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC, OSHA.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
25
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Carbon dioxide
CAS Number
124-38-9
DTXSID
DTXSID4027028
Molecular Formula
CO2
InChI Key
CURLTUGMZLYLDI-UHFFFAOYSA-N
Monoisotopic Mass
43.989829
Synonyms
CO2AER FixusAfter-dampCarbon oxide, di-CarbonicaCaswell No. 163EINECS 204-696-9EPA Pesticide Chemical Code 016601Anhydride carboniqueKohlendioxydKohlensaureUNII-142M471B3J
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Contains gas under pressure; may explode if heated |
| Short-term Effects | Rapid evaporation of the liquid may cause frostbite. Inhalation of high levels may cause effects on multiple organs. This may result in acidosis and impaired functions. Exposure at high concentrations could cause asphyxiation. See Notes. |
| Long-term Effects | The substance may have effects on the metabolism. This may result in impaired functions. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
6 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 5000 ppm (9000 mg/m³) | 5000 | 9000 | N |
| NIOSH | TWA | 5000 ppm (9000 mg/m³) | 5000 | 9000 | N |
| NIOSH | STEL | 30,000 ppm (54,000 mg/m³) | - | - | N |
| CAL/OSHA | TWA | 5000 ppm (9000 mg/m³) | 5000 | 9000 | N |
| CAL/OSHA | STEL | 30,000 ppm (54,000 mg/m³) | - | - | N |
| NIOSH | IDLH | 40,000 ppm | - | - | - |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
37 records
Propellants, non-motive (blowing agents)SolventBiocideFlavouring and nutrientProcessing aids not otherwise specifiedAntioxidantpH regulating agentHeat transferring agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
25 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| active_ingredient; Pesticides | MN Department of Agriculture Pesticide Sales Database | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| fracking; water | NY Department of Conservation | CPCat |
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 142M471B3J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 142M471B3J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 142M471B3J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 142M471B3J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CARBON DIOXIDE
ChEMBL Phase
3
Adverse Events
2
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E290 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Carbon dioxide?
Carbon dioxide appears on 10 regulatory/inventory lists including active_ingredient; Pesticides, active_ingredient; Europe; Pesticides, active_ingredient; Australia, and 7 more. Source: EPA CPDat.
What are the occupational exposure limits for Carbon dioxide?
Occupational exposure limits for Carbon dioxide are set by OSHA, NIOSH, CAL/OSHA. 6 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Carbon dioxide used in cosmetics?
Yes, Carbon dioxide is also indexed as a cosmetic ingredient under the name Carbon Dioxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Carbon dioxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Carbon dioxide used outside industrial chemicals?
Carbon dioxide also appears in cosmetics, pharmaceutical, food safety, cannabis databases.