Danger GHS08GHS05GHS09 NOAEL Data REACH Registered Cosmetic Ingredient

1-Octadecanamine

Also known as: Octadecylamine, 4-04-00-00825, Armeen 118d, BRN 0636111, EINECS 204-695-3 (+5 more)

CAS 124-30-1

1-Octadecanamine (CAS 124-30-1) is a chemical substance with GHS signal word Danger; key hazard signal: H304; H373 (gastro-intestinal tract, liver, immune system); H315; H318; H400; H410. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Stearamine →

SOURCE noael studies public
NOAEL studies
9
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
1-Octadecanamine
CAS Number
124-30-1
DTXSID
DTXSID1025801
Molecular Formula
C18H39N
InChI Key
REYJJPSVUYRZGE-UHFFFAOYSA-N
Monoisotopic Mass
269.30825
Synonyms
Octadecylamine4-04-00-00825Armeen 118dBRN 0636111EINECS 204-695-3Kemamine P990Noram SHOktadecylaminUNII-FFV58UNY7OStearyl amine

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1H304; H373 (gastro-intestinal tract, liver, immune system); H315; H318; H400; H410GHS08; GHS05; GHS09Danger

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is irritating to the eyes, skin and respiratory tract.
Routes of ExposureThe substance can be absorbed into the body by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
Anti-static agentNo specific technical functionProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 9 of 9 studies
ValueUnitEndpointRouteSpeciesSource
=1mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=0.38mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
FFV58UNY7OUNIIFDA UNII substance identifier--openFDA substances
FFV58UNY7OUNIIFDA UNII substance identifier--openFDA substances
FFV58UNY7OUNIIFDA UNII substance identifier--openFDA substances
FFV58UNY7OUNIIFDA UNII substance identifier--openFDA substances
15mg/kg bw/dayNOAELoraldogCOSMOS_DB
25mg/kg bw/dayNOAELoralratCOSMOS_DB
150mg/kg bw/dayNOAELoralratCOSMOS_DB

Showing 9 of 9 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredOctadecylamine204-695-3ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emulsifier
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL OCTADECYLAMINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the GHS hazard classification for 1-Octadecanamine?

1-Octadecanamine (CAS 124-30-1) is classified under EU CLP Annex VI as Asp. Tox. 1; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H304; H373 (gastro-intestinal tract, liver, immune system); H315; H318; H400; H410. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 1-Octadecanamine?

1-Octadecanamine has 9 NOAEL studies in the database. The lowest reported value is 0.38 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include 1-Octadecanamine?

1-Octadecanamine appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is 1-Octadecanamine used in cosmetics?

Yes, 1-Octadecanamine is also indexed as a cosmetic ingredient under the name Stearamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1-Octadecanamine come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Does 1-Octadecanamine have different safety status in cosmetics vs industrial chemicals?

1-Octadecanamine is classified GHS Danger (H304, H373, H315, H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.

Is 1-Octadecanamine used outside industrial chemicals?

1-Octadecanamine also appears in cosmetics, pharmaceutical, food safety databases.