What is the NOAEL for Sphingosine?
Sphingosine has 4 NOAEL studies in the database. The lowest reported value is NGZ37HRE42 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sphingosine
Also known as: (E)-2-Amino-4-octadecan-1,3-diol, 2-Aminooctadec-4-ene-1,3-diol
CAS 123-78-4
Sphingosine (CAS 123-78-4) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Sphingosine
CAS Number
123-78-4
DTXSID
DTXSID90861763
Molecular Formula
C18H37NO2
InChI Key
WWUZIQQURGPMPG-KRWOKUGFSA-N
Monoisotopic Mass
299.282429
Synonyms
(E)-2-Amino-4-octadecan-1,3-diol2-Aminooctadec-4-ene-1,3-diol
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| NGZ37HRE42 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGZ37HRE42 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGZ37HRE42 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NGZ37HRE42 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
barrier-lipid
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SPHINGOSINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Sphingosine?
Sphingosine appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Sphingosine used in cosmetics?
Yes, Sphingosine is also indexed as a cosmetic ingredient under the name Sphingosine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sphingosine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Sphingosine used outside industrial chemicals?
Sphingosine also appears in cosmetics, pharmaceutical databases.