Also known as: Propionaldehyde, EINECS 204-623-0, FEMA No. 2923, FEMA Number 2923, NCI-C61029 (+7 more)
CAS 123-38-6
Propanal (CAS 123-38-6) is a chemical substance with GHS signal word Danger; key hazard signal: H225; H335; H315; H319. Key regulatory status: REACH registered, 27 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, OSHA, EPA TRI.
Propanal is prohibited in EU cosmetics but has active industrial GHS classifications (H225, H335, H315, H319).
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Flam. Liq. 2; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2 | H225; H335; H315; H319 | GHS02; GHS07 | Danger |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The vapour is irritating to the eyes and respiratory tract. The substance is severely irritating to the eyes and skin. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its vapour and by ingestion. |
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| ACGIH | TWA | 20 ppm [1998] | 20 | - | N |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; emissions; Europe; nondetect; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; emissions; Europe; nondetect; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Road vehicles | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Commission | Fl@vis |
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| air; Batteries; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =8 | mg/m3 | BMCL (10 HEC) | inhalation | Rat | ToxValDB_IRIS |
| =133.006 | mg/m3 | BMCL (10) | inhalation | Rat | ToxValDB_TX_TCEQ |
| =8 | mg/m^3 | BMCL 10 (HEC) | inhalation | - | EPA_IRIS_iris_rfc_systems.csv |
| =12.1 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =6.1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| AMJ2B4M67V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AMJ2B4M67V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AMJ2B4M67V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 60.3466 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 62 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =4874.47 | mg/m3 | LEL | inhalation | Mouse | ToxValDB_ECHA_IUCLID |
| =4936.23 | mg/m3 | LEL | inhalation | Mouse | ToxValDB_ECHA_IUCLID |
| =6534.92 | mg/m3 | LEL | inhalation | Mouse | ToxValDB_ECHA_IUCLID |
| =16127.1 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =61762.3 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
| =318.313 | mg/m3 | LOAEL | inhalation | Human | ToxValDB_TX_TCEQ |
| =217 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =356.321 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =1781.6 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| >=3563.21 | mg/m3 | NOEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =0.008 | mg/m3 | RfC | inhalation | Human | ToxValDB_IRIS |
| =0.008 | mg/m^3 | RfC | inhalation | - | EPA_IRIS_iris_rfc_systems.csv |
Showing 22 of 22 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Propionaldehyde | 204-623-0 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| Propionaldehyde | - | - |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS food additive, ADI, and GRAS records where available.
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Propanal (CAS 123-38-6) is classified under EU CLP Annex VI as Flam. Liq. 2; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2 with signal word Danger. Hazard statements: H225; H335; H315; H319. Source: EU CLP Annex VI (ECHA).
Propanal has 22 NOAEL studies in the database. The lowest reported value is 0.008 mg/m3 via inhalation in Human. Source: ToxValDB_IRIS.
Propanal appears on 13 regulatory/inventory lists including Cons electronics mech appliances and machinery; detected; emissions; Europe, air; detected; emissions; Europe; Other direct contact consumer goods, air; emissions; Europe; nondetect; Other direct contact consumer goods, and 10 more. Source: EPA CPDat.
Occupational exposure limits for Propanal are set by ACGIH. 1 limit value from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Yes, Propanal is also indexed as a cosmetic ingredient under the name Propionaldehyde. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Propanal is prohibited in EU cosmetics but has active industrial GHS classifications (H225, H335, H315, H319).
Propanal also appears in cosmetics, pharmaceutical, food safety, cannabis databases.