What is the NOAEL for 2,6,8-Trimethyl-4-nonanone?
2,6,8-Trimethyl-4-nonanone has 6 NOAEL studies in the database. The lowest reported value is Q95W9K98Y8 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2,6,8-Trimethyl-4-nonanone
Also known as: 4-Nonanone, 2,6,8-trimethyl-, EINECS 204-607-3, Isobutyl heptyl ketone, NSC 66186
CAS 123-18-2
2,6,8-Trimethyl-4-nonanone (CAS 123-18-2) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
2,6,8-Trimethyl-4-nonanone
CAS Number
123-18-2
DTXSID
DTXSID7026998
Molecular Formula
C12H24O
InChI Key
GFWVDQCGGDBTBS-UHFFFAOYSA-N
Monoisotopic Mass
184.182715
Synonyms
4-Nonanone, 2,6,8-trimethyl-EINECS 204-607-3Isobutyl heptyl ketoneNSC 66186
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| Q95W9K98Y8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q95W9K98Y8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q95W9K98Y8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q95W9K98Y8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187270
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2,6,8-Trimethyl-4-nonanone?
2,6,8-Trimethyl-4-nonanone appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 2,6,8-Trimethyl-4-nonanone used in cosmetics?
Yes, 2,6,8-Trimethyl-4-nonanone is also indexed as a cosmetic ingredient under the name Trimethyl-4-nonanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,6,8-Trimethyl-4-nonanone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,6,8-Trimethyl-4-nonanone used outside industrial chemicals?
2,6,8-Trimethyl-4-nonanone also appears in cosmetics, pharmaceutical databases.