What is the NOAEL for Benzylhexadecyldimethylammonium chloride?
Benzylhexadecyldimethylammonium chloride has 4 NOAEL studies in the database. The lowest reported value is 85474O1N9D UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Benzylhexadecyldimethylammonium chloride
Also known as: Benzyl hexadecyl dimethyl ammonium chloride, Acinol, CDBAC, Dimethylhexadecylbenzyl ammonium chloride, EINECS 204-526-3 (+5 more)
CAS 122-18-9
Benzylhexadecyldimethylammonium chloride (CAS 122-18-9) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Benzylhexadecyldimethylammonium chloride is classified GHS Danger (H302, H312, H314, H318, H400, H410, H372, H401) in the chemicals database but is restricted in EU cosmetics at max 0.1%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Benzylhexadecyldimethylammonium chloride
CAS Number
122-18-9
DTXSID
DTXSID3041665
Molecular Formula
C25H46N.ClH
InChI Key
SXPWTBGAZSPLHA-UHFFFAOYSA-M
Monoisotopic Mass
396.339703
Synonyms
Benzyl hexadecyl dimethyl ammonium chlorideAcinolCDBACDimethylhexadecylbenzyl ammonium chlorideEINECS 204-526-3NSC 32942RodalonCetalconio cloruroCetalkonii chloridumUNII-85474O1N9D
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
Surfactant (surface active agent)BiocidePreservativeAnti-static agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 85474O1N9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 85474O1N9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 85474O1N9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 85474O1N9D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Cetalkonium chloride | 204-526-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.1%
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CETALKONIUM CHLORIDE
ChEMBL Phase
2
Adverse Events
28
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Benzylhexadecyldimethylammonium chloride?
Benzylhexadecyldimethylammonium chloride appears on 2 regulatory/inventory lists including pharmaceutical, active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is Benzylhexadecyldimethylammonium chloride used in cosmetics?
Yes, Benzylhexadecyldimethylammonium chloride is also indexed as a cosmetic ingredient under the name Cetalkonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzylhexadecyldimethylammonium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzylhexadecyldimethylammonium chloride have different safety status in cosmetics vs industrial chemicals?
Benzylhexadecyldimethylammonium chloride is classified GHS Danger (H302, H312, H314, H318, H400, H410, H372, H401) in the chemicals database but is restricted in EU cosmetics at max 0.1%.
Is Benzylhexadecyldimethylammonium chloride used outside industrial chemicals?
Benzylhexadecyldimethylammonium chloride also appears in cosmetics, pharmaceutical databases.