What is the NOAEL for Potassium oxide?
Potassium oxide has 5 NOAEL studies in the database. The lowest reported value is 15.83 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Potassium oxide
Also known as: Potassium oxide (K2O), EINECS 235-227-6, UNII-58D606078H
CAS 12136-45-7
Potassium oxide (CAS 12136-45-7) is a chemical substance. Key regulatory status: REACH registered, 30 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Potassium oxide is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H318).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
30
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Potassium oxide
CAS Number
12136-45-7
DTXSID
DTXSID3049754
Molecular Formula
2K.O
InChI Key
CHWRSCGUEQEHOH-UHFFFAOYSA-N
Monoisotopic Mass
93.922328
Synonyms
Potassium oxide (K2O)EINECS 235-227-6UNII-58D606078H
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Causes severe skin burns and eye damage |
| Short-term Effects | The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes. Medical observation is indicated. |
| Routes of Exposure | Serious local effects by all routes of exposure. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
15 records
pH regulating agentBinderFlux agentDegradant/impurityCatalyst
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
30 records
| List | Keyword | Source |
|---|---|---|
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| agricultural; applied; fruits_and_vegetables | USDA | United States Department of Agriculture (USDA) |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =15.83 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 58D606078H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 58D606078H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 58D606078H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 58D606078H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dipotassium oxide | 235-227-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Potassium oxide?
Potassium oxide appears on 3 regulatory/inventory lists including agricultural; applied; fruits_and_vegetables, agricultural; applied, drinking_water; Europe; manufacturing; plastic_additive. Source: EPA CPDat.
Is Potassium oxide used in cosmetics?
Yes, Potassium oxide is also indexed as a cosmetic ingredient under the name Potassium Oxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Potassium oxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Potassium oxide have different safety status in cosmetics vs industrial chemicals?
Potassium oxide is prohibited in EU cosmetics but has active industrial GHS classifications (H314, H318).
Is Potassium oxide used outside industrial chemicals?
Potassium oxide also appears in cosmetics, cannabis databases.