Danger GHS06 NOAEL Data REACH Registered Cosmetic Ingredient

Ammonium fluoride

Also known as: Ammonium fluoride ((NH4)F), EINECS 235-185-9, Ammonium fluorure, Fluorek amonowy, UNII-4QT928IM0A (+2 more)

CAS 12125-01-8

Ammonium fluoride (CAS 12125-01-8) is a chemical substance with GHS signal word Danger; key hazard signal: H331; H311; H301. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Ammonium Fluoride →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
Ammonium fluoride
CAS Number
12125-01-8
DTXSID
DTXSID6050463
Molecular Formula
FH.H3N
InChI Key
LDDQLRUQCUTJBB-UHFFFAOYSA-N
Monoisotopic Mass
37.032777
Synonyms
Ammonium fluoride ((NH4)F)EINECS 235-185-9Ammonium fluorureFluorek amonowyUNII-4QT928IM0AFluoruro amonicoNH4F

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *H331; H311; H301GHS06Danger

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe substance is irritating to the eyes, skin and respiratory tract. Corrosive on ingestion.
Long-term EffectsThe substance may have effects on the bones and teeth. This may result in fluorosis.
Routes of ExposureThe substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Pharmaceutical

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
=2.5mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
4QT928IM0AUNIIFDA UNII substance identifier--openFDA substances
4QT928IM0AUNIIFDA UNII substance identifier--openFDA substances
4QT928IM0AUNIIFDA UNII substance identifier--openFDA substances
4QT928IM0AUNIIFDA UNII substance identifier--openFDA substances

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredAmmonium fluoride235-185-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
0.15%
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Ammonium fluoride?

Ammonium fluoride (CAS 12125-01-8) is classified under EU CLP Annex VI as Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 * with signal word Danger. Hazard statements: H331; H311; H301. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Ammonium fluoride?

Ammonium fluoride has 5 NOAEL studies in the database. The lowest reported value is 2.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Ammonium fluoride?

Ammonium fluoride appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.

Is Ammonium fluoride used in cosmetics?

Yes, Ammonium fluoride is also indexed as a cosmetic ingredient under the name Ammonium Fluoride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ammonium fluoride come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Ammonium fluoride have different safety status in cosmetics vs industrial chemicals?

Ammonium fluoride is classified GHS Danger (H331, H311, H301) in the chemicals database but is restricted in EU cosmetics at max 0.15%.

Is Ammonium fluoride used outside industrial chemicals?

Ammonium fluoride also appears in cosmetics databases.