Also known as: 1-Butanone, 2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-
CAS 119313-12-1
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one (CAS 119313-12-1) is a chemical substance with GHS signal word Danger; key hazard signal: H360D; H400; H410. Key regulatory status: SVHC Candidate List, REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ECHA SVHC.
View cosmetic safety profile for Benzyl Dimethylamino Morpholinophenyl Butanone →
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one is prohibited in EU cosmetics but has active industrial GHS classifications (H360D, H400, H410).
CAS, identifiers, formula, and alternate names for the matched substance record.
Candidate List status and reason under the ECHA REACH SVHC program.
| Substance | Reason | Included |
|---|---|---|
| 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | Toxic for reproduction (Article 57c) | 16-Jan-2020 |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Repr. 1B; Aquatic Acute 1; Aquatic Chronic 1 | H360D; H400; H410 | GHS08; GHS09 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.82 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =1.175 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =2.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 413O6RKS6B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 413O6RKS6B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 413O6RKS6B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 413O6RKS6B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >=250 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| <=500 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =10 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 12 of 12 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone | 404-360-3 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one (CAS 119313-12-1) is classified under EU CLP Annex VI as Repr. 1B; Aquatic Acute 1; Aquatic Chronic 1 with signal word Danger. Hazard statements: H360D; H400; H410. Source: EU CLP Annex VI (ECHA).
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one has 12 NOAEL studies in the database. The lowest reported value is 0.82 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.
Yes, 2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one is listed on the ECHA REACH Candidate List as a Substance of Very High Concern. Reason: Toxic for reproduction (Article 57c). Source: ECHA SVHC Candidate List.
Yes, 2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one is also indexed as a cosmetic ingredient under the name Benzyl Dimethylamino Morpholinophenyl Butanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ECHA SVHC Candidate List, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one is prohibited in EU cosmetics but has active industrial GHS classifications (H360D, H400, H410).
2-Benzyl-2-(dimethylamino)-1-[4-(morpholin-4-yl)phenyl]butan-1-one also appears in cosmetics, pharmaceutical databases.