What is the NOAEL for 3,3,5-Trimethylcyclohexanol?
3,3,5-Trimethylcyclohexanol has 9 NOAEL studies in the database. The lowest reported value is 08CL3G94GH UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3,3,5-Trimethylcyclohexanol
Also known as: Cyclohexanol, 3,3,5-trimethyl-, 3-06-00-00115, BRN 2203314, Cyclonol, EINECS 204-122-7 (+8 more)
CAS 116-02-9
3,3,5-Trimethylcyclohexanol (CAS 116-02-9) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
3,3,5-Trimethylcyclohexanol
CAS Number
116-02-9
DTXSID
DTXSID9041815
Molecular Formula
C9H18O
InChI Key
BRRVXFOKWJKTGG-UHFFFAOYSA-N
Monoisotopic Mass
142.135765
Synonyms
Cyclohexanol, 3,3,5-trimethyl-3-06-00-00115BRN 2203314CyclonolEINECS 204-122-7Isophorol, dihydro-1-Methyl-3-dimethylcyclohexanol-5NSC 40083,3,5-Trimethyl-1-cyclohexanol3,5,5-TrimethylcyclohexanolUNII-08CL3G94GHdihydroisophorol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 08CL3G94GH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 08CL3G94GH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 08CL3G94GH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 08CL3G94GH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =3250 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3,3,5-Trimethylcyclohexanol?
3,3,5-Trimethylcyclohexanol appears on 3 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency. Source: EPA CPDat.
Is 3,3,5-Trimethylcyclohexanol used in cosmetics?
Yes, 3,3,5-Trimethylcyclohexanol is also indexed as a cosmetic ingredient under the name TRIMETHYLCYCLOHEXANOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,3,5-Trimethylcyclohexanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,3,5-Trimethylcyclohexanol used outside industrial chemicals?
3,3,5-Trimethylcyclohexanol also appears in cosmetics, cannabis databases.