What is the NOAEL for 2-Butyl-2-ethyl-1,3-propanediol?
2-Butyl-2-ethyl-1,3-propanediol has 11 NOAEL studies in the database. The lowest reported value is 5.3 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Butyl-2-ethyl-1,3-propanediol
Also known as: 1,3-Propanediol, 2-butyl-2-ethyl-, 4-01-00-02611, 3,3-Bis(hydroxymethyl)heptane, BRN 1737392, Caswell No. 129 (+6 more)
CAS 115-84-4
2-Butyl-2-ethyl-1,3-propanediol (CAS 115-84-4) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
11
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
2-Butyl-2-ethyl-1,3-propanediol
CAS Number
115-84-4
DTXSID
DTXSID8041400
Molecular Formula
C9H20O2
InChI Key
DSKYSDCYIODJPC-UHFFFAOYSA-N
Monoisotopic Mass
160.14633
Synonyms
1,3-Propanediol, 2-butyl-2-ethyl-4-01-00-026113,3-Bis(hydroxymethyl)heptaneBRN 1737392Caswell No. 129EINECS 204-111-7EPA Pesticide Chemical Code 0410032-Ethyl-2-butyl-1,3-propandeiol2-Ethyl-2-butyl-1,3-propanediolNSC 406603UNII-61P3KJ8K4Y
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
HumectantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 61P3KJ8K4Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61P3KJ8K4Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61P3KJ8K4Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61P3KJ8K4Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 15 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| =15 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =20 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB HESS |
| =150 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =15 | mg/kg bw/day | NOEL | oral | Rat | ECHA |
Showing 11 of 11 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-butyl-2-ethylpropanediol | 204-111-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL3185639
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2-Butyl-2-ethyl-1,3-propanediol?
2-Butyl-2-ethyl-1,3-propanediol appears on 1 regulatory/inventory list including detected; Europe; Toys and children's products. Source: EPA CPDat.
Is 2-Butyl-2-ethyl-1,3-propanediol used in cosmetics?
Yes, 2-Butyl-2-ethyl-1,3-propanediol is also indexed as a cosmetic ingredient under the name Butyl Ethyl Propanediol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Butyl-2-ethyl-1,3-propanediol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Butyl-2-ethyl-1,3-propanediol used outside industrial chemicals?
2-Butyl-2-ethyl-1,3-propanediol also appears in cosmetics, pharmaceutical databases.