NOAEL Data Cosmetic Ingredient

Bromophenol blue

Also known as: 5-19-03-00458, BRN 0061698, EINECS 204-086-2, 3',3'',5',5''-Tetrabromophenolsulfonephthalein, 3,3',5,5'-Tetrabromophenolsulfonphthalein (+3 more)

CAS 115-39-9

Bromophenol blue (CAS 115-39-9) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Bromphenol Blue →

SOURCE noael studies public
NOAEL studies
13
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
Bromophenol blue
CAS Number
115-39-9
DTXSID
DTXSID6041682
Molecular Formula
C19H10Br4O5S
InChI Key
UDSAIICHUKSCKT-UHFFFAOYSA-N
Monoisotopic Mass
665.698245
Synonyms
5-19-03-00458BRN 0061698EINECS 204-086-23',3'',5',5''-Tetrabromophenolsulfonephthalein3,3',5,5'-TetrabromophenolsulfonphthaleinTetrabromphenol BlueUNII-0R2969YC90bromophenol blue, sultone form

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
BiocideAntioxidant

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 13 of 13 studies
ValueUnitEndpointRouteSpeciesSource
4.74301705uMAC50--NTP_ICE_endocrine
20.8347568620169uMAC50--NTP_ICE_endocrine
1.325491978uMACC--NTP_ICE_endocrine
26.1726056233093uMACC--NTP_ICE_endocrine
-uL/min/10^6 cellsClint-HumanNTP_ICE_adme_parameters
0R2969YC90UNIIFDA UNII substance identifier--openFDA substances
0R2969YC90UNIIFDA UNII substance identifier--openFDA substances
0R2969YC90UNIIFDA UNII substance identifier--openFDA substances
0R2969YC90UNIIFDA UNII substance identifier--openFDA substances
-unitlessModel Score--NTP_ICE_endocrine
0.0128unitlessModel Score--NTP_ICE_endocrine
0.0461unitlessModel Score--NTP_ICE_endocrine
0.232unitlessModel Score--NTP_ICE_endocrine

Showing 13 of 13 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL BROMOPHENOL BLUE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Bromophenol blue?

Bromophenol blue has 13 NOAEL studies in the database. The lowest reported value is 0 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.

What regulatory lists include Bromophenol blue?

Bromophenol blue appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Bromophenol blue used in cosmetics?

Yes, Bromophenol blue is also indexed as a cosmetic ingredient under the name Bromphenol Blue. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bromophenol blue come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Bromophenol blue used outside industrial chemicals?

Bromophenol blue also appears in cosmetics, pharmaceutical databases.