What is the NOAEL for Benzene, (dimethoxymethyl)-?
Benzene, (dimethoxymethyl)- has 8 NOAEL studies in the database. The lowest reported value is W6T83K35CA UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Benzene, (dimethoxymethyl)-
Also known as: 4-07-00-00513, BRN 2044501, Dimethoxymethylbenzene, EINECS 214-413-0, FEMA No. 2128 (+2 more)
CAS 1125-88-8
Benzene, (dimethoxymethyl)- (CAS 1125-88-8) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for BENZALDEHYDE DIMETHYLACETAL →
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Benzene, (dimethoxymethyl)-
CAS Number
1125-88-8
DTXSID
DTXSID5061538
Molecular Formula
C9H12O2
InChI Key
HEVMDQBCAHEHDY-UHFFFAOYSA-N
Monoisotopic Mass
152.08373
Synonyms
4-07-00-00513BRN 2044501DimethoxymethylbenzeneEINECS 214-413-0FEMA No. 2128Toluene, alpha,alpha-dimethoxy-UNII-W6T83K35CA
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| W6T83K35CA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W6T83K35CA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W6T83K35CA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W6T83K35CA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =1220 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Benzene, (dimethoxymethyl)-?
Benzene, (dimethoxymethyl)- appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Benzene, (dimethoxymethyl)- used in cosmetics?
Yes, Benzene, (dimethoxymethyl)- is also indexed as a cosmetic ingredient under the name BENZALDEHYDE DIMETHYLACETAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzene, (dimethoxymethyl)- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Benzene, (dimethoxymethyl)- used outside industrial chemicals?
Benzene, (dimethoxymethyl)- also appears in cosmetics, food safety, cannabis databases.