What is the NOAEL for 1-Decanol?
1-Decanol has 31 NOAEL studies in the database. The lowest reported value is 129 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1-Decanol
Also known as: Decanol, C 10 alcohol, C10 alcohol, 4-01-00-01815, T-148 (+15 more)
CAS 112-30-1
1-Decanol (CAS 112-30-1) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
1-Decanol is classified GHS Danger (H315, H319, H411, H412, H335, H400, H304, H332) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
31
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
1-Decanol
CAS Number
112-30-1
DTXSID
DTXSID7021946
Molecular Formula
C10H22O
InChI Key
MWKFXSUHUHTGQN-UHFFFAOYSA-N
Monoisotopic Mass
158.167065
Synonyms
DecanolC 10 alcoholC10 alcohol4-01-00-01815T-148BRN 1735221Caswell No. 275An-Decatyl alcoholDECYL, N- ALCOHOLEINECS 203-956-9EPA Pesticide Chemical Code 079038Fatty alcohol(C10)
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system at high levels. |
| Long-term Effects | The substance defats the skin, which may cause dryness or cracking. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
25 records
Surfactant (surface active agent)Softener and conditionerDeodorizerViscosity modifierFlavouring and nutrientFragranceSolventPlasticizerLubricating agentFoamant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 31 of 31 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =129 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =176 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 89V4LX791F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89V4LX791F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89V4LX791F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89V4LX791F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2.05 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >71 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| >100 | mg/kg bw/day | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| >100000 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =1000 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =1000 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =10 | mmol/kg | NOEL | oral | Rat | ToxValDB_ECOTOX |
| 13.2 | % | Positive reaction | Dermal | Human | NTP_ICE_skin_irritation |
| 6.45 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 6.94 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 7.11 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 7.31 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 8.2 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 9.7 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 10.9 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 11.1 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 12 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 12.2 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 12.66 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 15.6 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 24.9 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 29.8 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
| 42.1 | % | Viability | Dermal | - | NTP_ICE_skin_irritation |
Showing 31 of 31 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Decan-1-ol | 203-956-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DECANOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1-Decanol?
1-Decanol appears on 8 regulatory/inventory lists including inert_ingredient; Pesticides, active_ingredient; Europe; Pesticides, IFRA Transparency, and 5 more. Source: EPA CPDat.
Is 1-Decanol used in cosmetics?
Yes, 1-Decanol is also indexed as a cosmetic ingredient under the name Decyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-Decanol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 1-Decanol have different safety status in cosmetics vs industrial chemicals?
1-Decanol is classified GHS Danger (H315, H319, H411, H412, H335, H400, H304, H332) in the chemicals database but is allowed in EU cosmetics.
Is 1-Decanol used outside industrial chemicals?
1-Decanol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.