What is the NOAEL for L-(+)-Arginine monohydrochloride?
L-(+)-Arginine monohydrochloride has 6 NOAEL studies in the database. The lowest reported value is 668.2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
L-(+)-Arginine monohydrochloride
Also known as: L-Arginine, hydrochloride (1:1), Arginine, monohydrochloride, L-, L-Arginine, monohydrochloride, Argamine, Arginine hydrochloride (+13 more)
CAS 1119-34-2
L-(+)-Arginine monohydrochloride (CAS 1119-34-2) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
L-(+)-Arginine monohydrochloride
CAS Number
1119-34-2
DTXSID
DTXSID20883650
Molecular Formula
C6H14N4O2.ClH
InChI Key
KWTQSFXGGICVPE-WCCKRBBISA-N
Monoisotopic Mass
210.088353
Synonyms
L-Arginine, hydrochloride (1:1)Arginine, monohydrochloride, L-L-Arginine, monohydrochlorideArgamineArginine hydrochlorideArginine monochlorideArginine monohydrochlorideArgiveneDetoxarginL-(+)-Arginine hydrochlorideL-Arginine hydrochlorideLevargin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =668.2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| F7LTH1E20Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F7LTH1E20Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F7LTH1E20Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F7LTH1E20Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =12000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (+)-L-arginine hydrochloride | 214-275-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ARGININE HYDROCHLORIDE
ChEMBL Phase
4
Adverse Events
6
Bioactivity
1
Frequently Asked Questions
Is L-(+)-Arginine monohydrochloride used in cosmetics?
Yes, L-(+)-Arginine monohydrochloride is also indexed as a cosmetic ingredient under the name Arginine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for L-(+)-Arginine monohydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is L-(+)-Arginine monohydrochloride used outside industrial chemicals?
L-(+)-Arginine monohydrochloride also appears in cosmetics, pharmaceutical databases.