What is the NOAEL for Hexyl octanoate?
Hexyl octanoate has 10 NOAEL studies in the database. The lowest reported value is 4 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Hexyl octanoate
Also known as: FEMA 2575, Octanoic acid, hexyl ester, 3-02-00-00794, BRN 1769635, EINECS 214-247-9 (+5 more)
CAS 1117-55-1
Hexyl octanoate (CAS 1117-55-1) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Hexyl octanoate
CAS Number
1117-55-1
DTXSID
DTXSID8047636
Molecular Formula
C14H28O2
InChI Key
PBGWNXWNCSSXCO-UHFFFAOYSA-N
Monoisotopic Mass
228.20893
Synonyms
FEMA 2575Octanoic acid, hexyl ester3-02-00-00794BRN 1769635EINECS 214-247-9FEMA No. 2575Hexyl caprylaten-Hexyl caprylateUNII-GU3S7YK802Hexyl octylate
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| GU3S7YK802 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GU3S7YK802 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GU3S7YK802 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GU3S7YK802 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3375 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 10 of 10 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
CHEMBL3182596
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Hexyl octanoate?
Hexyl octanoate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Hexyl octanoate used in cosmetics?
Yes, Hexyl octanoate is also indexed as a cosmetic ingredient under the name Hexyl Octanoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexyl octanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Hexyl octanoate used outside industrial chemicals?
Hexyl octanoate also appears in cosmetics, pharmaceutical, food safety databases.