What is the NOAEL for N-(2-Hydroxyethyl)octadecanamide?
N-(2-Hydroxyethyl)octadecanamide has 5 NOAEL studies in the database. The lowest reported value is 73.44 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
N-(2-Hydroxyethyl)octadecanamide
Also known as: Clindrol 200-MS, Comperlan HS, Cycloamide SM, EINECS 203-883-2, Loramine S 280 (+15 more)
CAS 111-57-9
N-(2-Hydroxyethyl)octadecanamide (CAS 111-57-9) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
N-(2-Hydroxyethyl)octadecanamide is classified GHS Danger (H315, H318, H411, H412) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
N-(2-Hydroxyethyl)octadecanamide
CAS Number
111-57-9
DTXSID
DTXSID9042178
Molecular Formula
C20H41NO2
InChI Key
OTGQIQQTPXJQRG-UHFFFAOYSA-N
Monoisotopic Mass
327.31373
Synonyms
Clindrol 200-MSComperlan HSCycloamide SMEINECS 203-883-2Loramine S 280Marlamid M 18NSC 3377Onyx Wax ELStearamylStearic ethylolamideStearic monoethanolamineStearoyl Monoethanolamide
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
Anti-static agentViscosity modifierFoamantThickening agentSurfactant (surface active agent)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - body hygiene - body wash | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =73.44 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 03XV449Q24 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 03XV449Q24 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 03XV449Q24 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 03XV449Q24 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-(2-hydroxyethyl)stearamide | 203-883-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
N-(2-HYDROXYETHYL)STEARAMIDE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include N-(2-Hydroxyethyl)octadecanamide?
N-(2-Hydroxyethyl)octadecanamide appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, CEDI, children; Europe; Personal care, and 2 more. Source: EPA CPDat.
Is N-(2-Hydroxyethyl)octadecanamide used in cosmetics?
Yes, N-(2-Hydroxyethyl)octadecanamide is also indexed as a cosmetic ingredient under the name STEARAMIDE MEA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-(2-Hydroxyethyl)octadecanamide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does N-(2-Hydroxyethyl)octadecanamide have different safety status in cosmetics vs industrial chemicals?
N-(2-Hydroxyethyl)octadecanamide is classified GHS Danger (H315, H318, H411, H412) in the chemicals database but is allowed in EU cosmetics.
Is N-(2-Hydroxyethyl)octadecanamide used outside industrial chemicals?
N-(2-Hydroxyethyl)octadecanamide also appears in cosmetics, pharmaceutical databases.