What is the NOAEL for 1,5-Pentanediol?
1,5-Pentanediol has 6 NOAEL studies in the database. The lowest reported value is 35 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,5-Pentanediol
Also known as: Microcare Emollient PTG, 4-01-00-02540, BRN 1560130, EINECS 203-854-4, alpha,omega-Pentanediol (+2 more)
CAS 111-29-5
1,5-Pentanediol (CAS 111-29-5) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
1,5-Pentanediol
CAS Number
111-29-5
DTXSID
DTXSID2041256
Molecular Formula
C5H12O2
InChI Key
ALQSHHUCVQOPAS-UHFFFAOYSA-N
Monoisotopic Mass
104.08373
Synonyms
Microcare Emollient PTG4-01-00-02540BRN 1560130EINECS 203-854-4alpha,omega-Pentanediol1,5-Pentylene glycolUNII-07UXZ0SCST
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
SolventHumectantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =35 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 07UXZ0SCST | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 07UXZ0SCST | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 07UXZ0SCST | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 07UXZ0SCST | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =12700 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pentane-1,5-diol | 203-854-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
1,5-PENTANEDIOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 1,5-Pentanediol?
1,5-Pentanediol appears on 1 regulatory/inventory list including children; Europe; Personal care. Source: EPA CPDat.
Is 1,5-Pentanediol used in cosmetics?
Yes, 1,5-Pentanediol is also indexed as a cosmetic ingredient under the name 1,5-Pentanediol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,5-Pentanediol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,5-Pentanediol used outside industrial chemicals?
1,5-Pentanediol also appears in cosmetics, pharmaceutical databases.