What is the NOAEL for Oleic acid isopropanolamide?
Oleic acid isopropanolamide has 8 NOAEL studies in the database. The lowest reported value is 2.35 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Oleic acid isopropanolamide
Also known as: 9-Octadecenamide, N-(2-hydroxypropyl)-, (9Z)-, 9-Octadecenamide, N-(2-hydroxypropyl)-, (Z)-, Oleamide, N-(2-hydroxypropyl)-, (9Z)-N-(2-Hydroxypropyl)-9-octadecenamide, N-(2-Hydroxypropyl)oleamide (+7 more)
CAS 111-05-7
Oleic acid isopropanolamide (CAS 111-05-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Oleic acid isopropanolamide is classified GHS Danger (H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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NOAEL studies
NOAEL studies
8
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Chemical inventory jurisdictions
Regulatory lists
0
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EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
18 fields
Name
Oleic acid isopropanolamide
CAS Number
111-05-7
DTXSID
DTXSID90883304
Molecular Formula
C21H41NO2
InChI Key
UDZAXLGLNUMCRX-KHPPLWFESA-N
Monoisotopic Mass
339.31373
Synonyms
9-Octadecenamide, N-(2-hydroxypropyl)-, (9Z)-9-Octadecenamide, N-(2-hydroxypropyl)-, (Z)-Oleamide, N-(2-hydroxypropyl)-(9Z)-N-(2-Hydroxypropyl)-9-octadecenamideN-(2-Hydroxypropyl)oleamideOleamide MIPAOleic monoisopropanolamideOleylmonoisopropanolamideSteinamid IPE 280Witcamide 619-Octadecenamide, N-isopropyl-,(z)-EC No.: 203-828-2
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
8 records
Anti-static agentViscosity modifierFoamantThickening agentSurfactant (surface active agent)
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2.35 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 63Y91GM18S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 63Y91GM18S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 63Y91GM18S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 63Y91GM18S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ~100 | mg/kg bw/day | LOAEL | oral | Rat | ECHA |
| ~300 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| ~1000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-(2-hydroxypropyl)oleamide | 203-828-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Frequently Asked Questions
Is Oleic acid isopropanolamide used in cosmetics?
Yes, Oleic acid isopropanolamide is also indexed as a cosmetic ingredient under the name OLEAMIDE MIPA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oleic acid isopropanolamide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Oleic acid isopropanolamide have different safety status in cosmetics vs industrial chemicals?
Oleic acid isopropanolamide is classified GHS Danger (H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Is Oleic acid isopropanolamide used outside industrial chemicals?
Oleic acid isopropanolamide also appears in cosmetics databases.