What is the NOAEL for Glutaric acid?
Glutaric acid has 14 NOAEL studies in the database. The lowest reported value is 11.52 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Glutaric acid
Also known as: Pentanedioic acid, 4-02-00-01934, BRN 1209725, EINECS 203-817-2, n-Pyrotartaric acid (+8 more)
CAS 110-94-1
Glutaric acid (CAS 110-94-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Glutaric acid is classified GHS Danger (H314, H318, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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NOAEL studies
NOAEL studies
14
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Glutaric acid
CAS Number
110-94-1
DTXSID
DTXSID2021654
Molecular Formula
C5H8O4
InChI Key
JFCQEDHGNNZCLN-UHFFFAOYSA-N
Monoisotopic Mass
132.042259
Synonyms
Pentanedioic acid4-02-00-01934BRN 1209725EINECS 203-817-2n-Pyrotartaric acidUNII-H849F7N00B1,3-Propanedicarboxylate1,5-PentanedioateGlutarateGlutarsaeurePentandioatePentandioic acid
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
WHO/JECFA
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes, skin and respiratory tract. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
pH regulating agentFlavouring and nutrientProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 14 of 14 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =11.52 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| H849F7N00B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H849F7N00B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H849F7N00B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| H849F7N00B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =6000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =2 | % diet | LOAEL | oral | Rat | ToxValDB HPVIS |
| =400 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB HPVIS |
| >=1 | % diet | NOAEL | oral | Rat | ToxValDB HPVIS |
| >=2 | % diet | NOAEL | oral | Dog | ToxValDB HPVIS |
| =125 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB HPVIS |
| >500 | mg/kg bw/day | NOAEL | oral | Rabbit | ToxValDB HPVIS |
| >=1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB HPVIS |
| =1300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB HPVIS |
Showing 14 of 14 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Glutaric acid | 203-817-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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ChEMBL / DailyMed
GLUTARATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Glutaric acid?
Glutaric acid appears on 3 regulatory/inventory lists including Europe, SCIL (9/2019), Canada; pharmaceutical. Source: EPA CPDat.
Is Glutaric acid used in cosmetics?
Yes, Glutaric acid is also indexed as a cosmetic ingredient under the name Glutaric Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Glutaric acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Glutaric acid have different safety status in cosmetics vs industrial chemicals?
Glutaric acid is classified GHS Danger (H314, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Is Glutaric acid used outside industrial chemicals?
Glutaric acid also appears in cosmetics, pharmaceutical, cannabis databases.