What is the NOAEL for 2-Methylundecanal?
2-Methylundecanal has 20 NOAEL studies in the database. The lowest reported value is 0 % via Dermal. Source: NTP_ICE_skin_sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Methylundecanal
Also known as: Undecanal, 2-methyl-, Aldehyde C-12, M.N.A., Aldehyde M.N.A., Aldehyde C-12 mna, BRN 1758291 (+11 more)
CAS 110-41-8
2-Methylundecanal (CAS 110-41-8) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
20
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
2-Methylundecanal
CAS Number
110-41-8
DTXSID
DTXSID9047629
Molecular Formula
C12H24O
InChI Key
NFAVNWJJYQAGNB-UHFFFAOYSA-N
Monoisotopic Mass
184.182715
Synonyms
Undecanal, 2-methyl-Aldehyde C-12, M.N.A.Aldehyde M.N.A.Aldehyde C-12 mnaBRN 1758291EINECS 203-765-0FEMA No. 2749Methyl n-nonyl acetaldehydeMethyl nonyl acetic aldehydeMethyl n-nonyl acetic aldehyde2-MethylhendecanalMethylnonylacetaldehyde
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 20 of 20 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 34.505 | ug/mL | CD86, EC150 | Dermal | - | NTP_ICE_skin_sensitization |
| =92.21 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =36.89 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 100 | % | Depletion Cys | Dermal | - | NTP_ICE_skin_sensitization |
| - | % | Depletion Lys | Dermal | - | NTP_ICE_skin_sensitization |
| 24.24 | uM | EC1.5 | Dermal | - | NTP_ICE_skin_sensitization |
| 10 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 10 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 10 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| 10 | % | EC3 | Dermal | Mouse | NTP_ICE_skin_sensitization |
| S94QNS2VY5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S94QNS2VY5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S94QNS2VY5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S94QNS2VY5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 178 | uM | IC50 | Dermal | - | NTP_ICE_skin_sensitization |
| 7.685 | ratio | Imax | Dermal | - | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 20 of 20 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-methylundecanal | 203-765-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3182849
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Methylundecanal?
2-Methylundecanal appears on 5 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.
Is 2-Methylundecanal used in cosmetics?
Yes, 2-Methylundecanal is also indexed as a cosmetic ingredient under the name 2-Methyldodecanal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Methylundecanal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Methylundecanal used outside industrial chemicals?
2-Methylundecanal also appears in cosmetics, pharmaceutical, food safety, cannabis databases.