NOAEL Data REACH Registered Cosmetic Ingredient

Isopropyl tetradecanoate

Also known as: Tetradecanoic acid, 1-methylethyl ester, Isopropyl myristate, Isopropyl myristate-PM, EC No.: 203-751-4, Isopropyl tetradecanoic acid (+15 more)

CAS 110-27-0

Isopropyl tetradecanoate (CAS 110-27-0) is a chemical substance. Key regulatory status: REACH registered, 22 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Isopropyl Myristate →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields

Name

Isopropyl tetradecanoate

CAS Number

110-27-0

DTXSID

DTXSID0026838

Molecular Formula

C17H34O2

InChI Key

AXISYYRBXTVTFY-UHFFFAOYSA-N

Monoisotopic Mass

270.25588

Synonyms

Tetradecanoic acid, 1-methylethyl esterIsopropyl myristateIsopropyl myristate-PMEC No.: 203-751-4Isopropyl tetradecanoic acidBRN 1781127Caswell No. 511ECrodamol I.P.M.Deltyl ExtraDeltylextraEINECS 203-751-4Emcol-IM

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records

FragranceSoftener and conditionerDeodorizerBinderSolventFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 22 records

List	Keyword	Source
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; Pesticides	EPA	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
detected; Europe; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - general moisturizing - hand/body lotion	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - liniment	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
IFRA Transparency	IFRA	IFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)
SCIL (9/2019)	USEPA	Safer Chemical Ingredients List
Canada; pharmaceutical	DrugBank	DrugBank
Canada; pharmaceutical	DrugBank	DrugBank
consumer_product	P&G	Proctor & Gamble
Europe	European Commission	Fl@vis
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe	Danish Environmental Protection Agency	Danish EPA
inert_ingredient; non_food_use; Pesticides	EPA	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 38 of 38 studies

Value	Unit	Endpoint	Route	Species	Source
247.1	ug/mL	CD54, EC200	Dermal	-	NTP ICE skin sensitization
>200	ug/mL	CD86, EC150	Dermal	-	NTP ICE skin sensitization
977.7	ug/mL	CD86, EC150	Dermal	-	NTP ICE skin sensitization
>1893.199	ug/mL	CD86, EC150	Dermal	-	NTP ICE skin sensitization
>1000	ug/mL	CV75	Dermal	-	NTP ICE skin sensitization
=23.5	mg/m3	DNEL systemic	inhalation	Human	ToxValDB GESTIS DNEL
5.9	%	Depletion Cys	Dermal	-	NTP ICE skin sensitization
-	%	Depletion Lys	Dermal	-	NTP ICE skin sensitization
-	unitless	Draize rabbit irritation score	Ocular	Rabbit	NTP ICE eye irritation
>2000	uM	EC1.5	Dermal	-	NTP ICE skin sensitization
44	%	EC3	Dermal	Mouse	NTP ICE skin sensitization
44	%	EC3	Dermal	Mouse	NTP ICE skin sensitization
44	%	EC3	Dermal	Mouse	NTP ICE skin sensitization
44	%	EC3	Dermal	Mouse	NTP ICE skin sensitization
4	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
0RE8K4LNJS	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RE8K4LNJS	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RE8K4LNJS	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RE8K4LNJS	UNII	FDA UNII substance identifier	-	-	openFDA substances
384.8	uM	IC50	Dermal	-	NTP ICE skin sensitization
1.2	ratio	Imax	Dermal	-	NTP ICE skin sensitization
-	%	Incidence of positive responses	Dermal	Human	NTP ICE skin sensitization
12960	ug/cm2	Induction dose per skin area	Dermal	Human	NTP ICE skin sensitization
-	%/sec	Intensity	Ocular	-	NTP ICE eye irritation
>180	s	Lag time	Ocular	-	NTP ICE eye irritation
-	unitless	Model Score	-	-	NTP ICE endocrine
>1000	mg/kg bw/day	NOEL	oral	Rat	ECHA
3.3	%	Positive reaction	Dermal	Human	NTP ICE skin irritation
3	unitless	Relative reliability score	Dermal	Human	NTP ICE skin sensitization
92.6	%	Viability	Dermal	-	NTP ICE skin irritation
103.7	%	Viability	Dermal	-	NTP ICE skin irritation
106.2	%	Viability	Dermal	-	NTP ICE skin irritation
112.48	%	Viability	Dermal	-	NTP ICE skin irritation
127.41	%	Viability	Dermal	-	NTP ICE skin irritation
105.5	%	Viability (18 hours)	Dermal	-	NTP ICE skin irritation
107.4	%	Viability (18 hours)	Dermal	-	NTP ICE skin irritation
71.9	%	Viability (42 hours)	Dermal	-	NTP ICE skin irritation
77.8	%	Viability (42 hours)	Dermal	-	NTP ICE skin irritation

Showing 38 of 38 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records

Status	Name	EC Number	Link
Registered	Isopropyl myristate	203-751-4	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed ISOPROPYL MYRISTATE

ChEMBL Phase

-1

Adverse Events

312

Bioactivity

View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Isopropyl tetradecanoate?

Isopropyl tetradecanoate has 38 NOAEL studies in the database. The lowest reported value is 0 % via Dermal. Source: NTP ICE skin sensitization.

What regulatory lists include Isopropyl tetradecanoate?

Isopropyl tetradecanoate appears on 15 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; Pesticides, detected; Europe; Other direct contact consumer goods, and 12 more. Source: EPA CPDat.

Is Isopropyl tetradecanoate used in cosmetics?

Yes, Isopropyl tetradecanoate is also indexed as a cosmetic ingredient under the name Isopropyl Myristate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Isopropyl tetradecanoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Isopropyl tetradecanoate used outside industrial chemicals?

Isopropyl tetradecanoate also appears in cosmetics, pharmaceutical, cannabis databases.