Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Triethylene glycol dimethacrylate

Also known as: 2-Propenoic acid, 2-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester, Triethyleneglycol dimethacrylate, 1,2-Bis(2-(methacryloyloxy)ethoxy)ethane, BRN 1797351, EINECS 203-652-6 (+3 more)

CAS 109-16-0

Triethylene glycol dimethacrylate (CAS 109-16-0) is a chemical substance with GHS signal word Warning; key hazard signal: H317. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Triethylene Glycol Dimethacrylate (TEGDMA) →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
Triethylene glycol dimethacrylate
CAS Number
109-16-0
DTXSID
DTXSID3029607
Molecular Formula
C14H22O6
InChI Key
HWSSEYVMGDIFMH-UHFFFAOYSA-N
Monoisotopic Mass
286.141638
Synonyms
2-Propenoic acid, 2-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) esterTriethyleneglycol dimethacrylate1,2-Bis(2-(methacryloyloxy)ethoxy)ethaneBRN 1797351EINECS 203-652-6Polyester TGM 3Triethylene dimethacrylateUNII-14I47YJ5EY

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Skin Sens. 1BH317GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 10 records
Softener and conditionerMonomersAdhesion/cohesion promoterHardenerChemical reaction regulator

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Europe; Personal care - nailsDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
=48.5mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
14I47YJ5EYUNIIFDA UNII substance identifier--openFDA substances
14I47YJ5EYUNIIFDA UNII substance identifier--openFDA substances
14I47YJ5EYUNIIFDA UNII substance identifier--openFDA substances
14I47YJ5EYUNIIFDA UNII substance identifier--openFDA substances
<9441mg/kg bwLD50oralRatNTP_ICE_acute_oral
=10837mg/kg bwLD50oralRatNTP_ICE_acute_oral
>11674mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2,2'-ethylenedioxydiethyl dimethacrylate203-652-6ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3187544
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Triethylene glycol dimethacrylate?

Triethylene glycol dimethacrylate (CAS 109-16-0) is classified under EU CLP Annex VI as Skin Sens. 1B with signal word Warning. Hazard statements: H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Triethylene glycol dimethacrylate?

Triethylene glycol dimethacrylate has 8 NOAEL studies in the database. The lowest reported value is 48.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Triethylene glycol dimethacrylate?

Triethylene glycol dimethacrylate appears on 1 regulatory/inventory list including Europe; Personal care - nails. Source: EPA CPDat.

Is Triethylene glycol dimethacrylate used in cosmetics?

Yes, Triethylene glycol dimethacrylate is also indexed as a cosmetic ingredient under the name Triethylene Glycol Dimethacrylate (TEGDMA). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Triethylene glycol dimethacrylate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Triethylene glycol dimethacrylate used outside industrial chemicals?

Triethylene glycol dimethacrylate also appears in cosmetics, pharmaceutical databases.