Also known as: 2-Propanol, 1-(dimethylamino)-, (±)-1-(Dimethylamino)-2-propanol, Dimethylaminoisopropanol, 4-04-00-01666, BRN 1209244 (+12 more)
CAS 108-16-7
Dimepranol (CAS 108-16-7) is a chemical substance with GHS signal word Danger; key hazard signal: H226; H302; H314. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Dimethyl Isopropanolamine →
Dimepranol is classified GHS Danger (H226, H302, H314) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
CAS, identifiers, formula, and alternate names for the matched substance record.
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Flam. Liq. 3; Acute Tox. 4 *; Skin Corr. 1B | H226; H302; H314 | GHS02; GHS07; GHS05 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| OX17195H4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OX17195H4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OX17195H4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OX17195H4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1739 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =240 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =750 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | NEL | oral | Rat | ToxValDB_EPA_TSCA_8e |
| =120 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =240 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =250 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 12 of 12 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-(dimethylamino)propan-2-ol | 203-556-4 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Dimepranol (CAS 108-16-7) is classified under EU CLP Annex VI as Flam. Liq. 3; Acute Tox. 4 *; Skin Corr. 1B with signal word Danger. Hazard statements: H226; H302; H314. Source: EU CLP Annex VI (ECHA).
Dimepranol has 12 NOAEL studies in the database. The lowest reported value is 2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Dimepranol appears on 1 regulatory/inventory list including pharmaceutical. Source: EPA CPDat.
Yes, Dimepranol is also indexed as a cosmetic ingredient under the name Dimethyl Isopropanolamine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Dimepranol is classified GHS Danger (H226, H302, H314) in the chemicals database but is restricted in EU cosmetics at max 0.5%.
Dimepranol also appears in cosmetics, pharmaceutical databases.