What is the NOAEL for Citronellyl formate?
Citronellyl formate has 16 NOAEL studies in the database. The lowest reported value is 4.94 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Citronellyl formate
Also known as: 6-Octen-1-ol, 3,7-dimethyl-, formate, 3,7-Dimethyloct-6-en-1-yl formate, 6-Octen-1-ol, 3,7-dimethyl-, 1-formate, 2-02-00-00032, BRN 1723215 (+13 more)
CAS 105-85-1
Citronellyl formate (CAS 105-85-1) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
16
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
24 fields
Name
Citronellyl formate
CAS Number
105-85-1
DTXSID
DTXSID1044772
Molecular Formula
C11H20O2
InChI Key
DZNVIZQPWLDQHI-UHFFFAOYSA-N
Monoisotopic Mass
184.14633
Synonyms
6-Octen-1-ol, 3,7-dimethyl-, formate3,7-Dimethyloct-6-en-1-yl formate6-Octen-1-ol, 3,7-dimethyl-, 1-formate2-02-00-00032BRN 1723215Citronellol formateCitronellyl methanoate2,6-Dimethyl-2-octen-8-yl formate3,7-Dimethyl-6-octen-1-yl formate3,7-Dimethyl-6-octen-1-yl methanoateEINECS 203-338-9EINECS 300-075-2
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
12 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 16 of 16 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =4.94 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 7B1MY2BRDK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7B1MY2BRDK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7B1MY2BRDK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7B1MY2BRDK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =8400 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1000 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =800 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_EFSA |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 16 of 16 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Citronellyl formate | 203-338-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3184928
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Citronellyl formate?
Citronellyl formate appears on 5 regulatory/inventory lists including air; Cleaning products and household care - air freshener; detected; emissions; Europe, IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.
Is Citronellyl formate used in cosmetics?
Yes, Citronellyl formate is also indexed as a cosmetic ingredient under the name Citronellyl Formate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Citronellyl formate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Citronellyl formate used outside industrial chemicals?
Citronellyl formate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.