Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

2-(Diethylamino)ethyl methacrylate

Also known as: 2-Propenoic acid, 2-methyl-, 2-(diethylamino)ethyl ester, BRN 1761794, Daktose B, Diethylaminoethyl methacrylate, EINECS 203-275-7 (+4 more)

CAS 105-16-8

2-(Diethylamino)ethyl methacrylate (CAS 105-16-8) is a chemical substance with GHS signal word Warning; key hazard signal: H332; H315; H319; H317. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Diethylaminoethyl Methacrylate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 15 fields
Name
2-(Diethylamino)ethyl methacrylate
CAS Number
105-16-8
DTXSID
DTXSID4026713
Molecular Formula
C10H19NO2
InChI Key
SJIXRGNQPBQWMK-UHFFFAOYSA-N
Monoisotopic Mass
185.141579
Synonyms
2-Propenoic acid, 2-methyl-, 2-(diethylamino)ethyl esterBRN 1761794Daktose BDiethylaminoethyl methacrylateEINECS 203-275-7(2-(Methacryloyloxy)ethyl)diethylamineNSC 144902-Diethylaminoethylester kyseliny methakryloveUNII-N5SI2E7HOU

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1H332; H315; H319; H317GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Softener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
CEDIFDAUnited States Food and Drug Administration (FDA)
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
=4.41mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
N5SI2E7HOUUNIIFDA UNII substance identifier--openFDA substances
N5SI2E7HOUUNIIFDA UNII substance identifier--openFDA substances
N5SI2E7HOUUNIIFDA UNII substance identifier--openFDA substances
N5SI2E7HOUUNIIFDA UNII substance identifier--openFDA substances
11mg/LLC50Inhalation-NTP_ICE_acute_inhalation
=4696mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2-(diethylamino)ethyl methacrylate203-275-7ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3182085
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for 2-(Diethylamino)ethyl methacrylate?

2-(Diethylamino)ethyl methacrylate (CAS 105-16-8) is classified under EU CLP Annex VI as Acute Tox. 4 *; Skin Irrit. 2; Eye Irrit. 2; Skin Sens. 1 with signal word Warning. Hazard statements: H332; H315; H319; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 2-(Diethylamino)ethyl methacrylate?

2-(Diethylamino)ethyl methacrylate has 7 NOAEL studies in the database. The lowest reported value is 4.41 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include 2-(Diethylamino)ethyl methacrylate?

2-(Diethylamino)ethyl methacrylate appears on 2 regulatory/inventory lists including CEDI, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is 2-(Diethylamino)ethyl methacrylate used in cosmetics?

Yes, 2-(Diethylamino)ethyl methacrylate is also indexed as a cosmetic ingredient under the name Diethylaminoethyl Methacrylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-(Diethylamino)ethyl methacrylate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-(Diethylamino)ethyl methacrylate used outside industrial chemicals?

2-(Diethylamino)ethyl methacrylate also appears in cosmetics, pharmaceutical databases.