Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

HC Violet no. 2

Also known as: UNII-639H4QR04O, 1-gamma-Hydroxypropylamino-2-nitro-4-bis(beta-hydroxyethyl)aminobenzene, 1-Propanol, 3-((4-(bis(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-, HC Violet 2, Imexine FAG

CAS 104226-19-9

HC Violet no. 2 (CAS 104226-19-9) is a chemical substance with GHS signal word Warning; key hazard signal: H317; H412. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for HC Violet No. 2 →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 11 fields

Name

HC Violet no. 2

CAS Number

104226-19-9

DTXSID

DTXSID60146352

Molecular Formula

C13H21N3O5

InChI Key

YHSOWKGIYXECIF-UHFFFAOYSA-N

Monoisotopic Mass

299.148121

Synonyms

UNII-639H4QR04O1-gamma-Hydroxypropylamino-2-nitro-4-bis(beta-hydroxyethyl)aminobenzene1-Propanol, 3-((4-(bis(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-HC Violet 2Imexine FAG

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Skin Sens. 1; Aquatic Chronic 3	H317; H412	GHS07	Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records

Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records

List	Keyword	Source
Europe; Personal care; restricted	European Commission	CosIng
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 24 of 24 studies

Value	Unit	Endpoint	Route	Species	Source
50	mg/kg bw/d	-	-	-	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
50	mg/kg bw/d	-	-	-	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
2500	mg/kg bw/d	-	oral	human	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
639H4QR04O	UNII	FDA UNII substance identifier	-	-	openFDA substances
639H4QR04O	UNII	FDA UNII substance identifier	-	-	openFDA substances
639H4QR04O	UNII	FDA UNII substance identifier	-	-	openFDA substances
639H4QR04O	UNII	FDA UNII substance identifier	-	-	openFDA substances
50	mg/kg bw/day	LOAEL	oral	rat	COSMOS_DB
=50	mg/kg bw/d	NOAEL	-	-	SCCS_vision_codex
=50	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=50	mg/kg bw/d	NOAEL	-	-	SCCS_vision_codex
=50	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=50	mg/kg bw/d	NOAEL	-	-	SCCS_vision_codex
=50	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=50	mg/kg bw/d	NOAEL	-	-	SCCS_vision_codex
=50	mg/kg bw	NOAEL	oral	rat	SCCS_vision_codex
=2500	mg/kg bw/d	NOAEL	oral	human	SCCS_vision_codex
=2500	mg/kg bw/d	NOAEL	oral	human	SCCS_vision_codex
=2500	mg/kg bw/d	NOAEL	oral	human	SCCS_vision_codex
=2500	mg/kg bw/d	NOAEL	oral	human	SCCS_vision_codex
=50	mg/kg bw	dermal absorption	oral	rat	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
=50	mg/kg bw	dermal absorption	oral	rat	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
50	mg/kg bw/d	dermal absorption	dermal	mouse	UnifiedCodex:SCCS_SHADOW:beta.noael_studies
50	mg/kg bw/d	dermal absorption	dermal	mouse	UnifiedCodex:SCCS_SHADOW:beta.noael_studies

Showing 24 of 24 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	3-((4-(bis(2-hydroxyethyl)amino)-2-nitrophenyl)amino)-1-propanol	410-910-3	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Frequently Asked Questions

What is the GHS hazard classification for HC Violet no. 2?

HC Violet no. 2 (CAS 104226-19-9) is classified under EU CLP Annex VI as Skin Sens. 1; Aquatic Chronic 3 with signal word Warning. Hazard statements: H317; H412. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for HC Violet no. 2?

HC Violet no. 2 has 24 NOAEL studies in the database. The lowest reported value is 50 mg/kg bw/d. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.

What regulatory lists include HC Violet no. 2?

HC Violet no. 2 appears on 2 regulatory/inventory lists including Europe; Personal care; restricted, children; Europe; Personal care. Source: EPA CPDat.

Is HC Violet no. 2 used in cosmetics?

Yes, HC Violet no. 2 is also indexed as a cosmetic ingredient under the name HC Violet No. 2. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for HC Violet no. 2 come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is HC Violet no. 2 used outside industrial chemicals?

HC Violet no. 2 also appears in cosmetics databases.