NOAEL Data REACH Registered Cosmetic Ingredient

Diethylene glycol monophenyl ether

Also known as: 2-(2-Phenoxyethoxy)ethanol, Phenoxydiglycol, Ethanol, 2-(2-phenoxyethoxy)-, BRN 2093125, Diethylene glycolphenyl ether (+5 more)

CAS 104-68-7

Diethylene glycol monophenyl ether (CAS 104-68-7) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for PEG-2 PHENYL ETHER →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
Diethylene glycol monophenyl ether
CAS Number
104-68-7
DTXSID
DTXSID0051528
Molecular Formula
C10H14O3
InChI Key
ZUAURMBNZUCEAF-UHFFFAOYSA-N
Monoisotopic Mass
182.094294
Synonyms
2-(2-Phenoxyethoxy)ethanolPhenoxydiglycolEthanol, 2-(2-phenoxyethoxy)-BRN 2093125Diethylene glycolphenyl etherEINECS 203-227-5NSC 406593Phenyl carbitolFenylkarbitolUNII-LZU6ET206Z

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Solvent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
artificial_saliva; detected; emissions; Europe; Toys and children's productsDanish Environmental Protection AgencyDanish EPA
CEDIFDAUnited States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
=10.6mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=42.9mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
LZU6ET206ZUNIIFDA UNII substance identifier--openFDA substances
LZU6ET206ZUNIIFDA UNII substance identifier--openFDA substances
LZU6ET206ZUNIIFDA UNII substance identifier--openFDA substances
LZU6ET206ZUNIIFDA UNII substance identifier--openFDA substances

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2-(2-phenoxyethoxy)ethanol203-227-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvents
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Diethylene glycol monophenyl ether?

Diethylene glycol monophenyl ether has 6 NOAEL studies in the database. The lowest reported value is 10.6 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Diethylene glycol monophenyl ether?

Diethylene glycol monophenyl ether appears on 3 regulatory/inventory lists including artificial_saliva; detected; emissions; Europe; Toys and children's products, CEDI, Indirect additives food contact (10/2018). Source: EPA CPDat.

Is Diethylene glycol monophenyl ether used in cosmetics?

Yes, Diethylene glycol monophenyl ether is also indexed as a cosmetic ingredient under the name PEG-2 PHENYL ETHER. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Diethylene glycol monophenyl ether come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Diethylene glycol monophenyl ether have different safety status in cosmetics vs industrial chemicals?

Diethylene glycol monophenyl ether is classified GHS Danger (H302, H318, H319) in the chemicals database but is allowed in EU cosmetics.

Is Diethylene glycol monophenyl ether used outside industrial chemicals?

Diethylene glycol monophenyl ether also appears in cosmetics databases.