NOAEL Data REACH Registered Cosmetic Ingredient

Formic acid, phenylmethyl ester

Also known as: 4-06-00-02262, Benzyl alcohol, formate, Benzyl methanoate, BRN 2041319, EINECS 203-214-4 (+7 more)

CAS 104-57-4

Formic acid, phenylmethyl ester (CAS 104-57-4) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Benzyl Formate →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
5
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
Formic acid, phenylmethyl ester
CAS Number
104-57-4
DTXSID
DTXSID5059298
Molecular Formula
C8H8O2
InChI Key
UYWQUFXKFGHYNT-UHFFFAOYSA-N
Monoisotopic Mass
136.052429
Synonyms
4-06-00-02262Benzyl alcohol, formateBenzyl methanoateBRN 2041319EINECS 203-214-4FEMA No. 2145NSC 8049Phenylmethyl formateBenzyl formiatAmeisensaeurebenzylesterBenzylester kyseliny mravenciUNII-79GJF97O0Y

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Canada; pharmaceuticalDrugBankDrugBank
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
79GJF97O0YUNIIFDA UNII substance identifier--openFDA substances
79GJF97O0YUNIIFDA UNII substance identifier--openFDA substances
79GJF97O0YUNIIFDA UNII substance identifier--openFDA substances
79GJF97O0YUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
6480ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=1400mg/kg bwLD50oralRatNTP_ICE_acute_oral
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredBenzyl formate203-214-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Formic acid, phenylmethyl ester?

Formic acid, phenylmethyl ester has 8 NOAEL studies in the database. The lowest reported value is 79GJF97O0Y UNII. Source: openFDA substances.

What regulatory lists include Formic acid, phenylmethyl ester?

Formic acid, phenylmethyl ester appears on 5 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.

Is Formic acid, phenylmethyl ester used in cosmetics?

Yes, Formic acid, phenylmethyl ester is also indexed as a cosmetic ingredient under the name Benzyl Formate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Formic acid, phenylmethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Formic acid, phenylmethyl ester used outside industrial chemicals?

Formic acid, phenylmethyl ester also appears in cosmetics, cannabis databases.