NOAEL Data REACH Registered Cosmetic Ingredient

3-Phenylprop-2-en-1-yl acetate

Also known as: 2-Propen-1-ol, 3-phenyl-, acetate, 1-Acetoxy-3-phenyl-2-propene, BRN 2046000, NSC 46109, 1-phenyl-3-acetoxyprop-1-ene (+8 more)

CAS 103-54-8

3-Phenylprop-2-en-1-yl acetate (CAS 103-54-8) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Cinnamyl Acetate →

SOURCE noael studies public
NOAEL studies
12
SOURCE chemical inventory jurisdictions
Regulatory lists
6
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 19 fields
Name
3-Phenylprop-2-en-1-yl acetate
CAS Number
103-54-8
DTXSID
DTXSID2044765
Molecular Formula
C11H12O2
InChI Key
WJSDHUCWMSHDCR-UHFFFAOYSA-N
Monoisotopic Mass
176.08373
Synonyms
2-Propen-1-ol, 3-phenyl-, acetate1-Acetoxy-3-phenyl-2-propeneBRN 2046000NSC 461091-phenyl-3-acetoxyprop-1-ene3-Phenyl-2-propenyl acetate3-phenyl-2-propen-1-ol acetate3-phenyl-2-propen-1-yl acetate3-phenylallyl acetateCinnamyl acetatePhCH=CHCH2OAcacetic acid cinnamyl ester

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 36 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 6 records
ListKeywordSource
Australia; Food and drug - smoking-related productsNew Zealand ESRCPCat
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
detected; Europe; Personal care - sexual wellnessDanish Environmental Protection AgencyDanish EPA
detected; Europe; Personal care - sexual wellnessDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 12 of 12 studies
ValueUnitEndpointRouteSpeciesSource
=2.35mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
LFJ36XSV8KUNIIFDA UNII substance identifier--openFDA substances
LFJ36XSV8KUNIIFDA UNII substance identifier--openFDA substances
LFJ36XSV8KUNIIFDA UNII substance identifier--openFDA substances
LFJ36XSV8KUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
3240ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=3300mg/kg bwLD50oralRatNTP_ICE_acute_oral
=275mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=275mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
=275mg/kg bw/dayNOAELoral: feedRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 12 of 12 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredCinnamyl acetate203-121-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 3-Phenylprop-2-en-1-yl acetate?

3-Phenylprop-2-en-1-yl acetate has 12 NOAEL studies in the database. The lowest reported value is 2.35 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include 3-Phenylprop-2-en-1-yl acetate?

3-Phenylprop-2-en-1-yl acetate appears on 5 regulatory/inventory lists including Australia; Food and drug - smoking-related products, IFRA Transparency, Europe, and 2 more. Source: EPA CPDat.

Is 3-Phenylprop-2-en-1-yl acetate used in cosmetics?

Yes, 3-Phenylprop-2-en-1-yl acetate is also indexed as a cosmetic ingredient under the name Cinnamyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3-Phenylprop-2-en-1-yl acetate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 3-Phenylprop-2-en-1-yl acetate used outside industrial chemicals?

3-Phenylprop-2-en-1-yl acetate also appears in cosmetics, food safety, cannabis databases.