What is the NOAEL for Parbenate?
Parbenate has 5 NOAEL studies in the database. The lowest reported value is 1.65 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Parbenate
Also known as: Benzoic acid, 4-(dimethylamino)-, ethyl ester, EINECS 233-634-3, UNII-829S8D3Y0X, N,N-Dimethylbenzocaine, Darocur EBD (+3 more)
CAS 10287-53-3
Parbenate (CAS 10287-53-3) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Parbenate is classified GHS Danger (H360, H360F, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Parbenate
CAS Number
10287-53-3
DTXSID
DTXSID2044763
Molecular Formula
C11H15NO2
InChI Key
FZUGPQWGEGAKET-UHFFFAOYSA-N
Monoisotopic Mass
193.110279
Synonyms
Benzoic acid, 4-(dimethylamino)-, ethyl esterEINECS 233-634-3UNII-829S8D3Y0XN,N-DimethylbenzocaineDarocur EBDGenocure EPDKayacure EPAEthyl-p-Dimethylaminobenzoate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
Stabilizing agentPhotosensitizersChemical reaction regulator
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| artificial_saliva; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1.65 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 829S8D3Y0X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 829S8D3Y0X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 829S8D3Y0X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 829S8D3Y0X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ethyl 4-dimethylaminobenzoate | 233-634-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185245
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Parbenate?
Parbenate appears on 2 regulatory/inventory lists including artificial_saliva; detected; emissions; Europe; Other direct contact consumer goods, Cons electronics mech appliances and machinery; detected; Europe. Source: EPA CPDat.
Is Parbenate used in cosmetics?
Yes, Parbenate is also indexed as a cosmetic ingredient under the name Butyl Undecenoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Parbenate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Parbenate have different safety status in cosmetics vs industrial chemicals?
Parbenate is classified GHS Danger (H360, H360F, H411) in the chemicals database but is allowed in EU cosmetics.
Is Parbenate used outside industrial chemicals?
Parbenate also appears in cosmetics, pharmaceutical databases.