What is the NOAEL for Alpha-Amylcinnamyl alcohol?
Alpha-Amylcinnamyl alcohol has 22 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Alpha-Amylcinnamyl alcohol
Also known as: 3-06-00-02542, alpha-Amylcinnamic alcohol, 2-Amyl-3-phenyl-2-propen-1-ol, 2-Benzylideneheptanol, 2-Benzylidene-1-heptanol (+7 more)
CAS 101-85-9
Alpha-Amylcinnamyl alcohol (CAS 101-85-9) is a chemical substance. Key regulatory status: 14 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
22
SOURCE
chemical inventory jurisdictions
Regulatory lists
14
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Alpha-Amylcinnamyl alcohol
CAS Number
101-85-9
DTXSID
DTXSID2049393
Molecular Formula
C14H20O
InChI Key
LIPHCKNQPJXUQF-UHFFFAOYSA-N
Monoisotopic Mass
204.151415
Synonyms
3-06-00-02542alpha-Amylcinnamic alcohol2-Amyl-3-phenyl-2-propen-1-ol2-Benzylideneheptanol2-Benzylidene-1-heptanolBRN 3127316BuxinolEINECS 202-982-8FEMA No. 2065alpha-Pentylcinnamyl alcohol2-(Phenylmethylene)-1-heptanolUNII-DKB52S61GU
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
19 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
14 records
| List | Keyword | Source |
|---|---|---|
| Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
| Cleaning products and household care - air freshener; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bath salts | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; nondetect; Personal care | Danish Environmental Protection Agency | Danish EPA |
| consumer_product; Europe; nondetect | Danish Environmental Protection Agency | Danish EPA |
| consumer_product; detected; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care; restricted | European Commission | CosIng |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 22 of 22 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 17.7 | ug/mL | CD54, EC200 | Dermal | - | NTP_ICE_skin_sensitization |
| 14.78 | ug/mL | CD86, EC150 | Dermal | - | NTP_ICE_skin_sensitization |
| 40.26 | ug/mL | CV70 | Dermal | - | NTP_ICE_skin_sensitization |
| 46.1 | ug/mL | CV75 | Dermal | - | NTP_ICE_skin_sensitization |
| 31.2 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 8 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| >2000 | uM | EC1.5 | Dermal | - | NTP_ICE_skin_sensitization |
| DKB52S61GU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DKB52S61GU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DKB52S61GU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DKB52S61GU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 44.1 | uM | IC50 | Dermal | - | NTP_ICE_skin_sensitization |
| 0.98 | ratio | Imax | Dermal | - | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.282 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3543 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 5039 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 5184 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 19650 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| =4000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 5 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 22 of 22 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Alpha-Amylcinnamyl alcohol?
Alpha-Amylcinnamyl alcohol appears on 11 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 8 more. Source: EPA CPDat.
Is Alpha-Amylcinnamyl alcohol used in cosmetics?
Yes, Alpha-Amylcinnamyl alcohol is also indexed as a cosmetic ingredient under the name Amylcinnamyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Alpha-Amylcinnamyl alcohol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Alpha-Amylcinnamyl alcohol used outside industrial chemicals?
Alpha-Amylcinnamyl alcohol also appears in cosmetics, cannabis databases.