What is the NOAEL for Aluminum sesquisulfate?
Aluminum sesquisulfate has 19 NOAEL studies in the database. The lowest reported value is 3 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Aluminum sesquisulfate
Also known as: Aluminum sulfate, Aluminum sulfate (3:2), Caswell No. 031A, Dialuminum sulphate, EINECS 233-135-0 (+14 more)
CAS 10043-01-3
Aluminum sesquisulfate (CAS 10043-01-3) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Aluminum sesquisulfate is classified GHS Danger (H290, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Aluminum sesquisulfate
CAS Number
10043-01-3
DTXSID
DTXSID2040317
Molecular Formula
2Al.3H2O4S
InChI Key
DIZPMCHEQGEION-UHFFFAOYSA-H
Monoisotopic Mass
347.865216
Synonyms
Aluminum sulfateAluminum sulfate (3:2)Caswell No. 031ADialuminum sulphateEINECS 233-135-0EPA Pesticide Chemical Code 013906Filter AlumNSC 54563Papermaker's AlumPearl AlumPickle AlumSulfuric acid, aluminum(3+) salt (3:2)
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Causes serious eye irritation May cause respiratory irritation Toxic to aquatic life |
| Short-term Effects | The substance is severely irritating to the eyes, respiratory tract and gastrointestinal tract. The substance is mildly irritating to the skin. |
| Long-term Effects | The substance may have effects on the central nervous system. This may result in impaired functions. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
AstringentDeodorizerAntiperspirantpH regulating agentProcessing aids not otherwise specifiedChelating agentEmulsifierDyeStabilizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =13.4 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| I7T908772F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7T908772F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7T908772F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I7T908772F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.05 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| 0.2 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >233.5 | mg/kg bw/day | LEL | dermal | Pig | ToxValDB_ECHA_IUCLID |
| =2335 | mg/kg bw/day | LEL | dermal | Mouse | ToxValDB_ECHA_IUCLID |
| =150 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1250 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1500 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =40 | mg/kg bw/day | NOAEL | injection | Mouse | ToxValDB_ECHA_IUCLID |
| =300 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =317 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =342 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1850 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =10265 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 19 of 19 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Aluminium sulphate | 233-135-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ALUMINUM SULFATE ANHYDROUS
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E520 — ADI: 1 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Aluminum sesquisulfate?
Aluminum sesquisulfate appears on 5 regulatory/inventory lists including active_ingredient; Europe; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 2 more. Source: EPA CPDat.
Is Aluminum sesquisulfate used in cosmetics?
Yes, Aluminum sesquisulfate is also indexed as a cosmetic ingredient under the name Aluminum Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Aluminum sesquisulfate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Aluminum sesquisulfate have different safety status in cosmetics vs industrial chemicals?
Aluminum sesquisulfate is classified GHS Danger (H290, H318) in the chemicals database but is allowed in EU cosmetics.
Is Aluminum sesquisulfate used outside industrial chemicals?
Aluminum sesquisulfate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.