Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Benzyl alcohol

Also known as: Benzenemethanol, 4-06-00-02222, BRN 0878307, EINECS 202-859-9, EPA Pesticide Chemical Code 009502 (+15 more)

CAS 100-51-6

Benzyl alcohol (CAS 100-51-6) is a chemical substance with GHS signal word Warning; key hazard signal: H302; H319; H317. Key regulatory status: REACH registered, 60 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Benzyl Alcohol →

SOURCE noael studies public

NOAEL studies

100

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields

Name

Benzyl alcohol

CAS Number

100-51-6

DTXSID

DTXSID5020152

Molecular Formula

C7H8O

InChI Key

WVDDGKGOMKODPV-UHFFFAOYSA-N

Monoisotopic Mass

108.057515

Synonyms

Benzenemethanol4-06-00-02222BRN 0878307EINECS 202-859-9EPA Pesticide Chemical Code 009502FEMA No. 2137Methanol, phenyl-NCI-C06111Alcool benzilicoUNII-LKG8494WBHUlesfia.alpha.-hydroxytoluene

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1B	H302; H319; H317	GHS07	Warning

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
Short-term Effects	The aerosol is irritating to the eyes and skin. The substance may cause effects on the nervous system.
Long-term Effects	Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure	The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records

PreservativeSolventFragranceEmulsifierBiocidePharmaceuticalViscosity modifierDeodorizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 60 records

List	Keyword	Source
Europe; Personal care - hair styling and care - shampoo-dandruff	Danish Environmental Protection Agency	Danish EPA
Europe	Danish Environmental Protection Agency	Danish EPA
Europe; Specialty occupational products	Danish Environmental Protection Agency	Danish EPA
drinking_water; Europe; manufacturing; plastic_additive	Belgaqua	CPCat
active_ingredient; Pesticides	State of California	State of California
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
pharmaceutical	FDA	United States Food and Drug Administration (FDA)
pharmaceutical	FDA	United States Food and Drug Administration (FDA)
Cleaning products and household care - air freshener; Cleaning products and household care - laundry and fabric treatment - fabric deodorizer; detected; Europe; Vehicle - car interior - auto air freshener	Danish Environmental Protection Agency	Danish EPA
artificial_saliva; detected; emissions; Europe; Toys and children's products	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care - body hygiene - hand soap	Danish Environmental Protection Agency	Danish EPA
active_ingredient; Europe; Pesticides	Commission of the European Communities	CPCat
active_ingredient; animal_products; Europe; pharmaceutical; residue	EU	CPCat
air; detected; emissions; Europe; Vehicle - car interior	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Vehicle - car interior	Danish Environmental Protection Agency	Danish EPA
Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; Europe	Danish Environmental Protection Agency	Danish EPA
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe	Danish Environmental Protection Agency	Danish EPA
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - specialized bath products - bath salts	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - general moisturizing - hand/body lotion	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - body hygiene - body wash	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - hair styling and care - shampoo	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - specialized bath products - bubble bath	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care - dental care - toothpaste	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
children; detected; Europe; Personal care - body hygiene - body wash; Personal care - fragrance; Personal care - general moisturizing - hand/body lotion; Personal care - hair styling and care - shampoo; Personal care - specialized bath products - bath salts	Danish Environmental Protection Agency	Danish EPA
children; detected; Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Personal care - make-up and related	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Personal care - make-up and related	Danish Environmental Protection Agency	Danish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe	Danish Environmental Protection Agency	Danish EPA
Cleaning products and household care - dishwasher and dishes; Cleaning products and household care - general household cleaning; Cleaning products and household care - laundry and fabric treatment; detected; Europe; Other direct contact consumer goods	Danish Environmental Protection Agency	Danish EPA
consumer_product; detected; Europe	Danish Environmental Protection Agency	Danish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe	Danish Environmental Protection Agency	Danish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe	Danish Environmental Protection Agency	Danish EPA
detected; Europe; Personal care - sexual wellness	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 100 studies

Value	Unit	Endpoint	Route	Species	Source
1072	mg/m3	-	-	rabbit	UnifiedCodex:CIR:beta.noael_studies
=4	mg/kg bw/day	ADI	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
=4	mg/kg bw/day	ADI	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
<=5	mg/kg bw/day	ADI (group)	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
<=5	mg/kg bw/day	ADI (group)	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
766.6	ug/mL	CD86, EC150	Dermal	-	NTP_ICE_skin_sensitization
1000	ug/mL	CV75	Dermal	-	NTP_ICE_skin_sensitization
range6.9	%	Concentration, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range11.2	%	Concentration, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range13.75	%	Concentration, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range2.5	%	Concentration, one positive response	Dermal	Human	NTP_ICE_skin_sensitization
=22	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
=25.8	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
2.1	%	Depletion Cys	Dermal	-	NTP_ICE_skin_sensitization
8	%	Depletion Lys	Dermal	-	NTP_ICE_skin_sensitization
31	unitless	Draize rabbit irritation score	Ocular	Rabbit	NTP_ICE_eye_irritation
<964.51	uM	EC1.5	Dermal	-	NTP_ICE_skin_sensitization
>2000	uM	EC1.5	Dermal	-	NTP_ICE_skin_sensitization
4000	uM	EC1.5	Dermal	-	NTP_ICE_skin_sensitization
1	unitless	EPA Classification	Ocular	Rabbit	NTP_ICE_eye_irritation
LKG8494WBH	UNII	FDA UNII substance identifier	-	-	openFDA substances
LKG8494WBH	UNII	FDA UNII substance identifier	-	-	openFDA substances
LKG8494WBH	UNII	FDA UNII substance identifier	-	-	openFDA substances
LKG8494WBH	UNII	FDA UNII substance identifier	-	-	openFDA substances
2	unitless	GHS Classification	Ocular	Rabbit	NTP_ICE_eye_irritation
>2400	uM	IC50	Dermal	-	NTP_ICE_skin_sensitization
1.23	ratio	Imax	Dermal	-	NTP_ICE_skin_sensitization
1.232	ratio	Imax	Dermal	-	NTP_ICE_skin_sensitization
1.929	ratio	Imax	Dermal	-	NTP_ICE_skin_sensitization
-	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range0.9	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range1.8	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range8.7	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
3543	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
6480	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
8858	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
17720	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
23620	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
range8150	ug/cm2	Induction dose per skin area, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range13228	ug/cm2	Induction dose per skin area, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range16240	ug/cm2	Induction dose per skin area, 5% incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
range2953	ug/cm2	Induction dose per skin area, one positive response	Dermal	Human	NTP_ICE_skin_sensitization
range4724	ug/cm2	Induction dose per skin area, one positive response	Dermal	Human	NTP_ICE_skin_sensitization
0.27	%/sec	Intensity	Ocular	-	NTP_ICE_eye_irritation
>4.178	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
>5.4	mg/L	LC50	Inhalation	-	NTP_ICE_acute_inhalation
>1230	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
<3120	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=100	mg/kg bw/day	LEL	dermal	Rat	ToxValDB_ECHA_IUCLID
>=200	mg/kg bw/day	LEL	oral	Mouse	ToxValDB_ECHA_IUCLID

Showing 50 of 100 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Benzyl alcohol	202-859-9	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

1% as preservative in cosmetics (Annex V); labelling required >10 ppm leave-on / >100 ppm rinse-off as fragrance

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL BENZYL ALCOHOL

ChEMBL Phase

Adverse Events

Bioactivity

View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E1519 — ADI: 5 mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the GHS hazard classification for Benzyl alcohol?

Benzyl alcohol (CAS 100-51-6) is classified under EU CLP Annex VI as Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1B with signal word Warning. Hazard statements: H302; H319; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Benzyl alcohol?

Benzyl alcohol has 100 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.

What regulatory lists include Benzyl alcohol?

Benzyl alcohol appears on 41 regulatory/inventory lists including Europe; Personal care - hair styling and care - shampoo-dandruff, Europe, Europe; Specialty occupational products, and 38 more. Source: EPA CPDat.

Is Benzyl alcohol used in cosmetics?

Yes, Benzyl alcohol is also indexed as a cosmetic ingredient under the name Benzyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Benzyl alcohol come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Benzyl alcohol used outside industrial chemicals?

Benzyl alcohol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.