Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Benzyl alcohol

Also known as: Benzenemethanol, 4-06-00-02222, BRN 0878307, EINECS 202-859-9, EPA Pesticide Chemical Code 009502 (+15 more)

CAS 100-51-6

Benzyl alcohol (CAS 100-51-6) is a chemical substance with GHS signal word Warning; key hazard signal: H302; H319; H317. Key regulatory status: REACH registered, 60 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.

View cosmetic safety profile for Benzyl Alcohol →

SOURCE noael studies public
NOAEL studies
100
SOURCE chemical inventory jurisdictions
Regulatory lists
60
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
Benzyl alcohol
CAS Number
100-51-6
DTXSID
DTXSID5020152
Molecular Formula
C7H8O
InChI Key
WVDDGKGOMKODPV-UHFFFAOYSA-N
Monoisotopic Mass
108.057515
Synonyms
Benzenemethanol4-06-00-02222BRN 0878307EINECS 202-859-9EPA Pesticide Chemical Code 009502FEMA No. 2137Methanol, phenyl-NCI-C06111Alcool benzilicoUNII-LKG8494WBHUlesfia.alpha.-hydroxytoluene

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1BH302; H319; H317GHS07Warning

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records
FieldValue
Short-term EffectsThe aerosol is irritating to the eyes and skin. The substance may cause effects on the nervous system.
Long-term EffectsRepeated or prolonged contact may cause skin sensitization.
Routes of ExposureThe substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
PreservativeSolventFragranceEmulsifierBiocidePharmaceuticalViscosity modifierDeodorizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 60 records
ListKeywordSource
Europe; Personal care - hair styling and care - shampoo-dandruffDanish Environmental Protection AgencyDanish EPA
EuropeDanish Environmental Protection AgencyDanish EPA
Europe; Specialty occupational productsDanish Environmental Protection AgencyDanish EPA
drinking_water; Europe; manufacturing; plastic_additiveBelgaquaCPCat
active_ingredient; PesticidesState of CaliforniaState of California
inert_ingredient; non_food_use; PesticidesEPACPCat
pharmaceuticalFDAUnited States Food and Drug Administration (FDA)
pharmaceuticalFDAUnited States Food and Drug Administration (FDA)
Cleaning products and household care - air freshener; Cleaning products and household care - laundry and fabric treatment - fabric deodorizer; detected; Europe; Vehicle - car interior - auto air freshenerDanish Environmental Protection AgencyDanish EPA
artificial_saliva; detected; emissions; Europe; Toys and children's productsDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - body hygiene - hand soapDanish Environmental Protection AgencyDanish EPA
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat
active_ingredient; animal_products; Europe; pharmaceutical; residueEUCPCat
air; detected; emissions; Europe; Vehicle - car interiorDanish Environmental Protection AgencyDanish EPA
detected; Europe; Vehicle - car interiorDanish Environmental Protection AgencyDanish EPA
Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; EuropeDanish Environmental Protection AgencyDanish EPA
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; EuropeDanish Environmental Protection AgencyDanish EPA
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; EuropeDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - specialized bath products - bath saltsDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - general moisturizing - hand/body lotionDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - body hygiene - body washDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - hair styling and care - shampooDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - specialized bath products - bubble bathDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - dental care - toothpasteDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; detected; Europe; Personal care - body hygiene - body wash; Personal care - fragrance; Personal care - general moisturizing - hand/body lotion; Personal care - hair styling and care - shampoo; Personal care - specialized bath products - bath saltsDanish Environmental Protection AgencyDanish EPA
children; detected; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
detected; Europe; Personal care - make-up and relatedDanish Environmental Protection AgencyDanish EPA
detected; Europe; Personal care - make-up and relatedDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; EuropeDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - dishwasher and dishes; Cleaning products and household care - general household cleaning; Cleaning products and household care - laundry and fabric treatment; detected; Europe; Other direct contact consumer goodsDanish Environmental Protection AgencyDanish EPA
consumer_product; detected; EuropeDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; EuropeDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; EuropeDanish Environmental Protection AgencyDanish EPA
detected; Europe; Personal care - sexual wellnessDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 100 studies
ValueUnitEndpointRouteSpeciesSource
1072mg/m3--rabbitUnifiedCodex:CIR:beta.noael_studies
=4mg/kg bw/dayADI-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
=4mg/kg bw/dayADI-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
<=5mg/kg bw/dayADI (group)-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
<=5mg/kg bw/dayADI (group)-ConsumersEFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
766.6ug/mLCD86, EC150Dermal-NTP_ICE_skin_sensitization
1000ug/mLCV75Dermal-NTP_ICE_skin_sensitization
range6.9%Concentration, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range11.2%Concentration, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range13.75%Concentration, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range2.5%Concentration, one positive responseDermalHumanNTP_ICE_skin_sensitization
=22mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
=25.8mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
2.1%Depletion CysDermal-NTP_ICE_skin_sensitization
8%Depletion LysDermal-NTP_ICE_skin_sensitization
31unitlessDraize rabbit irritation scoreOcularRabbitNTP_ICE_eye_irritation
<964.51uMEC1.5Dermal-NTP_ICE_skin_sensitization
>2000uMEC1.5Dermal-NTP_ICE_skin_sensitization
4000uMEC1.5Dermal-NTP_ICE_skin_sensitization
1unitlessEPA ClassificationOcularRabbitNTP_ICE_eye_irritation
LKG8494WBHUNIIFDA UNII substance identifier--openFDA substances
LKG8494WBHUNIIFDA UNII substance identifier--openFDA substances
LKG8494WBHUNIIFDA UNII substance identifier--openFDA substances
LKG8494WBHUNIIFDA UNII substance identifier--openFDA substances
2unitlessGHS ClassificationOcularRabbitNTP_ICE_eye_irritation
>2400uMIC50Dermal-NTP_ICE_skin_sensitization
1.23ratioImaxDermal-NTP_ICE_skin_sensitization
1.232ratioImaxDermal-NTP_ICE_skin_sensitization
1.929ratioImaxDermal-NTP_ICE_skin_sensitization
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range0.9%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range1.8%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range8.7%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
3543ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
6480ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
8858ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
17720ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
23620ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
range8150ug/cm2Induction dose per skin area, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range13228ug/cm2Induction dose per skin area, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range16240ug/cm2Induction dose per skin area, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
range2953ug/cm2Induction dose per skin area, one positive responseDermalHumanNTP_ICE_skin_sensitization
range4724ug/cm2Induction dose per skin area, one positive responseDermalHumanNTP_ICE_skin_sensitization
0.27%/secIntensityOcular-NTP_ICE_eye_irritation
>4.178mg/LLC50Inhalation-NTP_ICE_acute_inhalation
>5.4mg/LLC50Inhalation-NTP_ICE_acute_inhalation
>1230mg/kg bwLD50oralRatNTP_ICE_acute_oral
<3120mg/kg bwLD50oralRatNTP_ICE_acute_oral
=100mg/kg bw/dayLELdermalRatToxValDB_ECHA_IUCLID
>=200mg/kg bw/dayLELoralMouseToxValDB_ECHA_IUCLID

Showing 50 of 100 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredBenzyl alcohol202-859-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
1% as preservative in cosmetics (Annex V); labelling required >10 ppm leave-on / >100 ppm rinse-off as fragrance
Category
preservative
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL BENZYL ALCOHOL
ChEMBL Phase
4
Adverse Events
0
Bioactivity
3
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E1519 — ADI: 5 mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the GHS hazard classification for Benzyl alcohol?

Benzyl alcohol (CAS 100-51-6) is classified under EU CLP Annex VI as Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1B with signal word Warning. Hazard statements: H302; H319; H317. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Benzyl alcohol?

Benzyl alcohol has 100 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.

What regulatory lists include Benzyl alcohol?

Benzyl alcohol appears on 41 regulatory/inventory lists including Europe; Personal care - hair styling and care - shampoo-dandruff, Europe, Europe; Specialty occupational products, and 38 more. Source: EPA CPDat.

Is Benzyl alcohol used in cosmetics?

Yes, Benzyl alcohol is also indexed as a cosmetic ingredient under the name Benzyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Benzyl alcohol come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Benzyl alcohol used outside industrial chemicals?

Benzyl alcohol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.