What is the NOAEL for 4-Anisic acid?
4-Anisic acid has 4 NOAEL studies in the database. The lowest reported value is 4SB6Y7DMM3 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
4-Anisic acid
Also known as: Benzoic acid, 4-methoxy-, Dermosoft 688, 4-Acetylanisole, 4-10-00-00346, Anisic acid, p-isomer (+7 more)
CAS 100-09-4
4-Anisic acid (CAS 100-09-4) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
4-Anisic acid
CAS Number
100-09-4
DTXSID
DTXSID4059205
Molecular Formula
C8H8O3
InChI Key
ZEYHEAKUIGZSGI-UHFFFAOYSA-N
Monoisotopic Mass
152.047344
Synonyms
Benzoic acid, 4-methoxy-Dermosoft 6884-Acetylanisole4-10-00-00346Anisic acid, p-isomerANISIC ACID, PARABRN 0508910EINECS 202-818-5Kyselina 4-methoxybenzoovaUNII-4SB6Y7DMM34-Methoxybenzoatep-Methoxybenzoate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
DeodorizerFlavouring and nutrientFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Commission | Fl@vis |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4SB6Y7DMM3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4SB6Y7DMM3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4SB6Y7DMM3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4SB6Y7DMM3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | p-anisic acid | 202-818-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
p-ANISIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 4-Anisic acid?
4-Anisic acid appears on 5 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe; Personal care, and 2 more. Source: EPA CPDat.
Is 4-Anisic acid used in cosmetics?
Yes, 4-Anisic acid is also indexed as a cosmetic ingredient under the name p-Anisic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Anisic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Anisic acid used outside industrial chemicals?
4-Anisic acid also appears in cosmetics, pharmaceutical, cannabis databases.