EFSA toxicology reference values
(1R,2S,5R)-Menthyl salicylate
(1R,2S,5R)-Menthyl salicylate (CAS 89-46-3). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
(1R,2S,5R)-Menthyl salicylate is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate 21 flavouring substance in the Flavouring Group Evaluation 9, Revision 4 (FGE.09Rev4), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev4, includes the assessment of four additional flavouring substances, p-menthan-3-one [FL-no: 07.059], 2,6,6-trimethylcyclohex-2-en-1-one [FL-no: 07.202], lpiperitone [FL-no: 07.255] and menthol 1-and 2-propylene glycol carbonate [FL-no: 09.843]. The present flavouring group evaluation deals with 21 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate one flavouring substance in the Flavouring Group Evaluation 9, Revision 3 (FGE.09Rev3), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The flavouring substance belongs to chemical group 08, Annex I of the Commission Regulation (EC) No 1565/2000. The present flavouring group evaluation therefore deals with 17 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 16 flavouring substances in the Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 16 flavouring substances belong to chemical group 21, Annex I of the Commission Regulation (EC) No 1565/2000. The present flavouring group evaluation deals with 16 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 15 flavouring substances in the Flavouring Group Evaluation 09, Revision 1 (FGE.09Rev1), using the procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 15 flavouring substances belong to chemical groups 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present flavouring group evaluation deals with 15 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 24 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 22 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 6 (FGE.09Rev6), using the Procedure referred to in Commission Regulation (EC) No 1565/2000 "(hereinafter 'the Procedure')". These flavouring substances belong to chemical groups 8, 25 and 30 of Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev6, includes the assessment of one additional candidate substance, trans-3-methyl-2-(2-pentenyl)-2-cyclopenten-1-one [FL-no: 07.219], which was not included in FGE.09Rev5. This substance is an alpha,beta-unsaturated carbonyl, for which concern for genotoxicity was ruled out in FGE.212Rev3. |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel is asked to evaluate ten flavouring substances in the Flavouring Group Evaluation FGE.09, using the procedure as referred to in the Commission Regulation EC No 1565/2000. These ten flavouring substances belong to chemical groups 8 and 25, Annex I of the Commission Regulation EC No 1565/2000. The present Flavouring Group Evaluation deals with nine secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols, and one ester of a phenol carboxylic acid and a secondary alicyclic alcohol. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission,the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 21 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 5 (FGE.09Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate one flavouring substance in the Flavouring Group Evaluation 9, Revision 3 (FGE.09Rev3), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The flavouring substance belongs to chemical group 08, Annex I of the Commission Regulation (EC) No 1565/2000. The present flavouring group evaluation therefore deals with 17 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Genetic Toxicity | - | - | - | Following a request from the European Commission,the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 21 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 5 (FGE.09Rev5), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 22 flavouring substances in the Flavouring Group Evaluation (FGE) 9, Revision 6 (FGE.09Rev6), using the Procedure referred to in Commission Regulation (EC) No 1565/2000 "(hereinafter 'the Procedure')". These flavouring substances belong to chemical groups 8, 25 and 30 of Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev6, includes the assessment of one additional candidate substance, trans-3-methyl-2-(2-pentenyl)-2-cyclopenten-1-one [FL-no: 07.219], which was not included in FGE.09Rev5. This substance is an alpha,beta-unsaturated carbonyl, for which concern for genotoxicity was ruled out in FGE.212Rev3. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 16 flavouring substances in the Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 16 flavouring substances belong to chemical group 21, Annex I of the Commission Regulation (EC) No 1565/2000. The present flavouring group evaluation deals with 16 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate 21 flavouring substance in the Flavouring Group Evaluation 9, Revision 4 (FGE.09Rev4), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These flavouring substances belong to chemical group 8, 25 and 30, Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.09, FGE.09Rev4, includes the assessment of four additional flavouring substances, p-menthan-3-one [FL-no: 07.059], 2,6,6-trimethylcyclohex-2-en-1-one [FL-no: 07.202], lpiperitone [FL-no: 07.255] and menthol 1-and 2-propylene glycol carbonate [FL-no: 09.843]. The present flavouring group evaluation deals with 21 secondary alicyclic saturated and unsaturated alcohols, ketones, one hemiketal ester and esters containing secondary alicyclic alcohols. The flavouring substances are structurally related to 27 flavouring substances evaluated at the 51st, 59th and 63rd meetings of the Joint FAO/WHO Expert Committee on Food Additives (the JECFA). |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for (1R,2S,5R)-Menthyl salicylate in cannabis?
(1R,2S,5R)-Menthyl salicylate does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for (1R,2S,5R)-Menthyl salicylate?
(1R,2S,5R)-Menthyl salicylate does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for (1R,2S,5R)-Menthyl salicylate?
(1R,2S,5R)-Menthyl salicylate has 7 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class I.
Is (1R,2S,5R)-Menthyl salicylate also regulated in cosmetics or food?
(1R,2S,5R)-Menthyl salicylate has a cosmetics ingredient cross-reference with EU status restricted. EFSA food/toxicology context is available on this page.