EFSA toxicology reference values
L-threonine
SOURCE
efsa openfoodtox 3 0 export repository
L-threonine (CAS 72-19-5). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
L-threonine is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 72-19-5
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
L-threonine
CAS number
72-19-5
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
72-19-5
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
L-threonine
CAS 72-19-5 / mono-constituent substance
C4H9NO3 / 7 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| Not deemed necessary | - | other: | - | - |
| critical study not identified | - | other: | - | - |
| margin of safety | - | consumers | - | - |
| Not deemed necessary | - | consumers | - | - |
| Incomplete dataset | - | other: | - | - |
| Incomplete dataset | - | other: | - | - |
| margin of safety | - | other: | - | - |
| margin of safety | - | other: | - | - |
| Incomplete dataset | - | other: | - | - |
| critical study not identified | - | other: | - | - |
| margin of safety | - | other: | - | - |
| Incomplete dataset | - | other: | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| Carcinogenicity_EU_PPP | - | - | - | According to Article 8 of Regulation (EC) No 1831/2003, EFSA shall determine whether the feed additive complies with the conditions laid down in Article 5. EFSA shall deliver an opinion on the safety for the target animals, consumer, user and the environment and the efficacy of the product L-threonineproduced by an Escherichia coli strain. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the European Food Safety Authority (EFSA) Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) was asked to deliver a scientific opinion on L-threonine produced by fermentation with genetically modified (GM) strains of Escherichia coli K-12 (NRRL B-30843, DSM 26131, KCCM11133P) or with a non-GM E. coli strain (DSM 25085) for all animal species. L-Threonine is an essential amino acid for all animal species. It is commonly considered the second and third limiting amino acid in cereal-based diets for pigs and poultry, respectively. It is widely used in the feed industry to optimise dietary protein. L-Threonine produced by E. coli DSM 26131 could not be assessed because of the insufficient molecular characterisation of the genetic modification, and the lack of data on both the absence of the production strain and its recombinant DNA from the final product. |
| Carcinogenicity_EU_PPP | - | - | - | According to Article 8 of Regulation (EC) No 1831/2003, EFSA shall determine whether the feed additive complies with the conditions laid down in Article 5. EFSA shall deliver an opinion on the safety for the target animal(s), consumer, user and the environment and the efficacy of the product L-threonine produced by fermentation using a genetically modified strain of Escherichia coli. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the safety and efficacy of the product L-threonine, technically pure, for all animal species. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-threonine (L-Threonine) produced by fermentation using a genetically modified (GM) Escherichia coli for all animal species. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-threonine, technically pure, produced by fermentation using the genetically modified (GM) strain Escherichia coli CGMCC 7.58 for all animal species. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission (EC), the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the safety of L-threonine, technically pure, produced by fermentation using the genetically modified strain Escherichia coli CGMCC 3703 for all animal species. In 2014, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA adopted an opinion on the safety and efficacy of L-threonine produced by fermentation with E. coli CGMCC 3703. The FEEDAP Panel could not conclude on the safety of that product for target animals, consumer, user and the environment because the genetic modification, including the presence/absence of recombinant DNA and of antibiotic resistance genes in the product, was insufficiently characterised. The applicant provided additional information in relation to the characterisation of the production microorganism, the characterisation of the additive and its stability. The FEEDAP Panel has performed the assessment of those new data following an approach in line with the principles laid down in Regulation (EC) No 429/2008 and the relevant guidance documents. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-threonine (L-Threonine) produced by fermentation using a genetically modified (GM) Escherichia coli for all animal species. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission (EC), the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the safety of L-threonine, technically pure, produced by fermentation using the genetically modified strain Escherichia coli CGMCC 3703 for all animal species. In 2014, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA adopted an opinion on the safety and efficacy of L-threonine produced by fermentation with E. coli CGMCC 3703. The FEEDAP Panel could not conclude on the safety of that product for target animals, consumer, user and the environment because the genetic modification, including the presence/absence of recombinant DNA and of antibiotic resistance genes in the product, was insufficiently characterised. The applicant provided additional information in relation to the characterisation of the production microorganism, the characterisation of the additive and its stability. The FEEDAP Panel has performed the assessment of those new data following an approach in line with the principles laid down in Regulation (EC) No 429/2008 and the relevant guidance documents. |
| Genetic Toxicity | - | - | - | According to Article 8 of Regulation (EC) No 1831/2003, EFSA shall determine whether the feed additive complies with the conditions laid down in Article 5. EFSA shall deliver an opinion on the safety for the target animals, consumer, user and the environment and the efficacy of the product L-threonineproduced by an Escherichia coli strain. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the European Food Safety Authority (EFSA) Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) was asked to deliver a scientific opinion on L-threonine produced by fermentation with genetically modified (GM) strains of Escherichia coli K-12 (NRRL B-30843, DSM 26131, KCCM11133P) or with a non-GM E. coli strain (DSM 25085) for all animal species. L-Threonine is an essential amino acid for all animal species. It is commonly considered the second and third limiting amino acid in cereal-based diets for pigs and poultry, respectively. It is widely used in the feed industry to optimise dietary protein. L-Threonine produced by E. coli DSM 26131 could not be assessed because of the insufficient molecular characterisation of the genetic modification, and the lack of data on both the absence of the production strain and its recombinant DNA from the final product. |
| Genetic Toxicity | - | - | - | According to Article 8 of Regulation (EC) No 1831/2003, EFSA shall determine whether the feed additive complies with the conditions laid down in Article 5. EFSA shall deliver an opinion on the safety for the target animal(s), consumer, user and the environment and the efficacy of the product L-threonine produced by fermentation using a genetically modified strain of Escherichia coli. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for L-threonine in cannabis?
L-threonine does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for L-threonine?
L-threonine does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for L-threonine?
L-threonine has 35 EFSA OpenFoodTox reference value rows in the cannabis database, including Not deemed necessary, critical study not identified, margin of safety, Incomplete dataset.
Is L-threonine also regulated in cosmetics or food?
L-threonine has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.