EFSA toxicology reference values
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (CAS 698-10-2). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
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Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 0.05 mg/kg | other: | - | - |
| MSI/FC | 0.05 mg/kg | other: | - | - |
| MSI/FC | 0.08 mg/kg | salmon | - | - |
| MSI/FC | 0.08 mg/kg | other: | - | - |
| MSI/FC | 0.08 mg/kg | other: | - | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| margin of safety | - | consumers | - | - |
| critical study not identified | - | consumers | - | other: |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| boiling point | - | - | - | experimental study |
| appearance / physical state / colour | - | - | - | experimental study |
| other: | - | - | - | relative density: (1.134 - 1.144) dimensionless |
| refractive index | - | - | - | refractive index: (1.486 - 1.493) dimensionless |
| water solubility | - | - | - | experimental study |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group Evaluation 217 (FGE.217). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate 12 flavouring substances in Flavouring Group Evaluation 217 (FGE.217) using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The FGE.217 concerned 12 substances, corresponding to subgroup 4.1 of FGE.19. The 12 substances are alpha,beta-unsaturated lactones [FL-no: 10.023, 10.030, 10.034, 10.036, 10.042, 10.043, 10.046, 10.054, 10.057, 10.060, 10.066 and 13.012], which by hydrolysis and oxidation gives rise to alpha,beta-unsaturated ketones, which is a structural alert for genotoxicity. |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 217 (FGE.217) concerns 12 substances. The 12 substances correspond to subgroup 4.1 of FGE.19. Ten of the substances are alpha,beta-unsaturated lactones, which by hydrolysis and oxidation give rise to alpha,beta-unsaturated ketones, and two substances are precursors for the two alpha,beta-unsaturated ketones 2,7-dimethyl-4-oxo-oct-5,7-dienoic acid and 3-methyl-6-(1-carboxyethyl)-2-cyclohexen-1-one, respectively. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 5-ethyl-3-hydroxy-4-methylfuran-2(5H)-one and 3-hydroxy-4,5-dimethylfuran-2(5H)-one (furanones and tetrahydrofurfuryl derivatives belonging to chemical group 13) when used as flavours for all animal species. These two additives are currently listed in the European Union database of flavouring substances and are authorised for use as flavours in food. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate 12 flavouring substances in Flavouring Group Evaluation 217 (FGE.217) using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The FGE.217 concerned 12 substances, corresponding to subgroup 4.1 of FGE.19. The 12 substances are alpha,beta-unsaturated lactones [FL-no: 10.023, 10.030, 10.034, 10.036, 10.042, 10.043, 10.046, 10.054, 10.057, 10.060, 10.066 and 13.012], which by hydrolysis and oxidation gives rise to alpha,beta-unsaturated ketones, which is a structural alert for genotoxicity. |
| Genetic Toxicity | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 217 (FGE.217) concerns 12 substances. The 12 substances correspond to subgroup 4.1 of FGE.19. Ten of the substances are alpha,beta-unsaturated lactones, which by hydrolysis and oxidation give rise to alpha,beta-unsaturated ketones, and two substances are precursors for the two alpha,beta-unsaturated ketones 2,7-dimethyl-4-oxo-oct-5,7-dienoic acid and 3-methyl-6-(1-carboxyethyl)-2-cyclohexen-1-one, respectively. |
| Genetic Toxicity | - | - | - | The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group Evaluation 217 (FGE.217). |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one in cannabis?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one has 9 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class III, margin of safety, critical study not identified.
Is 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one also regulated in cosmetics or food?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.