EFSA toxicology reference values
Malachite Green
Malachite Green (CAS 569-64-2). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
Malachite Green is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MOE | ca.950,000 other: | toddlers | 004f95a9-bada-41a8-8234-c642c13d3eec | - |
| MOE | ca.1,500,000 other: | adults | 004f95a9-bada-41a8-8234-c642c13d3eec | - |
| MOE | ca.2,100,000 other: | toddlers | c164bdd7-205a-4b84-a7aa-67b837e07f54 | - |
| MOE | ca.3,400,000 other: | adults | c164bdd7-205a-4b84-a7aa-67b837e07f54 | - |
| MOE | ca.4,800,000 other: | toddlers | 004f95a9-bada-41a8-8234-c642c13d3eec | - |
| MOE | ca.9,700,000 other: | adults | 004f95a9-bada-41a8-8234-c642c13d3eec | - |
| MOE | ca.11,000,000 other: | toddlers | c164bdd7-205a-4b84-a7aa-67b837e07f54 | - |
| MOE | ca.22,000,000 other: | adults | c164bdd7-205a-4b84-a7aa-67b837e07f54 | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| short-term repeated dose toxicity: oral | rat | oral: feed | 5.9 other: | - |
| chronic toxicity: oral | mouse | oral: feed | 13 other: | - |
| genetic toxicity in vivo, other | mouse | oral: gavage | - | DNA fragmentation (diphenylamine assay): Swiss albino female mice liver cells. Treatment; 27-543 mg/kg bw per day. |
| genetic toxicity in vivo, other | mouse | oral: feed | - | 32P-postlabelling analysis: Female B6C3F1 mouse liver DNA. Treatment: 100 and 600 mg/kg feed; Comment: Significant increase of adducts at both concentrations. |
| genetic toxicity in vivo, other | mouse | intraperitoneal | - | Micronucleus assay: Swiss albino female mice bone marrow; Concentration/treatment: ~ 4 mg/kg bw per day. Comment: Elevated ALT and AST activities; increased LPO and reactive aldehydes; depletion of GSH; modulation of antioxidative enzymes (GST, SOD, CAT, GPx, TrxR) Pretreatment with diphenylmethyl selenocyanate attenuated genotoxic effects. |
| genetic toxicity in vivo, other | mouse | oral: gavage | - | Chromosomal aberrations: Swiss albino female mice bone marrow and spermatocytes. Concentration/Treatment: 27-543 mg/kg bw per day for 7, 14, 21 and 28 days. Comment:Time and dose-dependent increase of chromosomal aberrations in bone marrow and spermatocytes. Depleted glutathione and increased free radical formation were observed. |
| genetic toxicity in vivo, other | rat | oral: feed | - | 32P-postlabelling analysis: Male F344 rat liver DNA. Treatment: 100 and 600 mg/kg feed; Comment: Significant increase of adducts at 600 mg/kg. |
| Carcinogenicity_EU_PPP | - | - | - | The European Commission requested EFSA to evaluate whether a reference point for action (RPA) of 2 lg/kg for the sum of malachite green (MG) and its major metabolite leucomalachite green (LMG) is adequate to protect public health. |
| Carcinogenicity_EU_PPP | - | - | - | The Commission asks EFSA to carry out a review of toxicological data available for Para Red and similar dyes (e.g. Sudan dyes, Rhodamine B, Orange II, etc. |
| Genetic Toxicity | - | - | - | The Commission asks EFSA to carry out a review of toxicological data available for Para Red and similar dyes (e.g. Sudan dyes, Rhodamine B, Orange II, etc. |
| Genetic Toxicity | - | - | - | The European Commission requested EFSA to evaluate whether a reference point for action (RPA) of 2 lg/kg for the sum of malachite green (MG) and its major metabolite leucomalachite green (LMG) is adequate to protect public health. |
| Genetic Toxicity | - | - | - | The European Commission requested EFSA to evaluate whether a reference point for action (RPA) of 2 lg/kg for the sum of malachite green (MG) and its major metabolite leucomalachite green (LMG) is adequate to protect public health. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for Malachite Green in cannabis?
Malachite Green does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for Malachite Green?
Malachite Green does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for Malachite Green?
Malachite Green has 8 EFSA OpenFoodTox reference value rows in the cannabis database, including MOE.
Is Malachite Green also regulated in cosmetics or food?
Malachite Green has a cosmetics ingredient cross-reference with EU status prohibited. EFSA food/toxicology context is available on this page.