EFSA toxicology reference values
Formaldehyde
SOURCE
efsa openfoodtox 3 0 export repository
Formaldehyde (CAS 50-00-0). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
Formaldehyde is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 50-00-0
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
Formaldehyde
CAS number
50-00-0
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
50-00-0
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
Formaldehyde
CAS 50-00-0 / mono-constituent substance
CH2O / 6 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| RfD | 0.2 mg/kg bw/day | consumers | ff43119d-75af-4282-828e-2556a6a0689c | other: |
| margin of safety | ca.1.5 other: | chicken for fattening | f7ae00f8-c9e4-4a81-915b-c7be8a00a28d | - |
| TDI | 150 µg/kg bw/day | consumers | ff43119d-75af-4282-828e-2556a6a0689c | other: |
| Incomplete dataset | - | other: | - | - |
| margin of safety | - | consumers | - | - |
| Incomplete dataset | - | other: | - | - |
| margin of safety | - | consumers | - | - |
| margin of safety | - | consumers | - | - |
| Incomplete dataset | - | other: | - | - |
| Incomplete dataset | - | other: | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| chronic toxicity: oral | rat | oral: drinking water | 15 other: | - |
| chronic toxicity: other route | rat | - | 15 mg/kg bw/day | - |
| toxic effects on livestock and pets | other: | other: | 990 other: | - |
| genetic toxicity in vitro, other | - | - | - | Different in vitro genotoxic effects such as structural chromosomal aberrations, sister-chromatid exchanges, gene mutations, DNA strand breaks, DNA protein crosslinks, and DNA repair deficiencies have been demonstrated in mammalian cells exposed to formaldehyde (BfR, 2006). However, due to the high reactivity and efficient cellular metabolism of formaldehyde, any in vivo genotoxicity potential may be limited to directly exposed tissues and may not be readily observed in more distant tissues (BfR, 2006). |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of formaldehyde as preservative in feedingstuffs for all animal species. |
| Carcinogenicity_EU_PPP | - | - | - | The Commission requests the European Food Safety Authority to issue an opinion on the safety for target species (poultry) of the additive formaldehyde. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. This consideration deals with 45 simple aliphatic and aromatic sulphides and thiols with and without an additional oxygenated functional group, which are in the Register and which were evaluated by the JECFA at its 53rd and 68th meetings. The Panel concluded that all the 45 substances in the JECFA flavouring groups of simple aliphatic and aromatic sulphides and thiols are structurally related to the aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by the European Food Safety Authority (EFSA) in the Flavouring Group Evaluation 08, Revision 1 (FGE.08Rev1). The 45 JECFA evaluated substances are distributed into eight subgroups of structurally related substances. The subgrouping is the same as used in FGE.08Rev1. This substance is here considered since hydrolysis product of dimercaptomethane [FL-no: 12.243]. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of formaldehyde as a feed hygiene substance in feedingstuffs for poultry and pigs. The additive formaldehyde is an aqueous solution of formaldehyde (34-38% w/w by specification) and methanol (0.5-15.0% v/v by specification), with a maximum concentration of formic acid of 0.05%. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of formaldehyde as preservative in feedingstuffs for all animal species. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food has been asked by the European Commission to issue an opinion on the safety in use of formaldehyde used as a preservative during the manufacture of food additives. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. This consideration deals with 45 simple aliphatic and aromatic sulphides and thiols with and without an additional oxygenated functional group, which are in the Register and which were evaluated by the JECFA at its 53rd and 68th meetings. The Panel concluded that all the 45 substances in the JECFA flavouring groups of simple aliphatic and aromatic sulphides and thiols are structurally related to the aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by the European Food Safety Authority (EFSA) in the Flavouring Group Evaluation 08, Revision 1 (FGE.08Rev1). The 45 JECFA evaluated substances are distributed into eight subgroups of structurally related substances. The subgrouping is the same as used in FGE.08Rev1. This substance is here considered since hydrolysis product of dimercaptomethane [FL-no: 12.243]. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food has been asked by the European Commission to issue an opinion on the safety in use of formaldehyde used as a preservative during the manufacture of food additives. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for Formaldehyde in cannabis?
Formaldehyde does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for Formaldehyde?
Formaldehyde does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for Formaldehyde?
Formaldehyde has 10 EFSA OpenFoodTox reference value rows in the cannabis database, including RfD, margin of safety, TDI, Incomplete dataset.
Is Formaldehyde also regulated in cosmetics or food?
Formaldehyde has a cosmetics ingredient cross-reference with EU status prohibited. EFSA food/toxicology context is available on this page.