EFSA toxicology reference values

3-Methyl-5-propylcyclohex-2-en-1-one

SOURCE efsa openfoodtox 3 0 export repository

3-Methyl-5-propylcyclohex-2-en-1-one (CAS 3720-16-9). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.

3-Methyl-5-propylcyclohex-2-en-1-one is a cannabis analyte contaminant represented in the cannabis public dataset.

CAS 3720-16-9 Cannabis Analyte

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE efsa substances
Analyte name
3-Methyl-5-propylcyclohex-2-en-1-one
CAS number
3720-16-9
Contaminant class
Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations
Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
3720-16-9

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE efsa openfoodtox 3 0 export repository
3-Methyl-5-propylcyclohex-2-en-1-one
CAS 3720-16-9 / mono-constituent substance
C10H16O / 6 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE efsa openfoodtox 3 0 export repository
DescriptorValuePopulationEndpointBody
TTC Cramer Class II 9 µg/kg bw/day consumers - -
TTC Cramer Class II 9 µg/kg bw/day consumers - -
TTC Cramer Class II 9 µg/kg bw/day consumers - -
TTC Cramer Class II 9 µg/kg bw/day consumers - other:
TTC Cramer Class II 9 µg/kg bw/day consumers - other:
TTC Cramer Class II 9 µg/kg bw/day consumers - -

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE efsa openfoodtox 3 0 export repository
EndpointSpeciesRouteEffectAssessment
Carcinogenicity_EU_PPP - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 24 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212, Revision 2. The Panel concluded in FGE.212, that the genotoxic potential could be ruled out for d-carvone [FL-no: 07.146] together with the structurally related l-carvone [FL-no: 07.147] as well as carveol and the carvyl derivatives [FL-no: 02.062, 09.143, 09.215 and 09.870]. Based on available genotoxicity data and new submitted genotoxicity data from the Industry, the Panel concluded that the genotoxic potential could be ruled out for the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the two vetiveryl derivatives [FL-no: 02.214 and 09.821] in FGE.212Rev1 and FGE.212Rev2, respectively. For the remaining five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 there is still a genotoxicity concern and additional data are required.
Carcinogenicity_EU_PPP - - - Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212. Based on available genotoxicity data and new genotoxicity data submitted by the Industry, the Panel concluded that genotoxic potential could be ruled out for the six carvone derivatives [FL-no: 02.062, 07.146, 07.147, 09.143, 09.215 and 09.870], the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 in FGE.212, FGE.212Rev1 and FGE.212Rev3, respectively. Two substances previously included in FGE.212Rev2, vetiverol and vetiveryl acetate [FL-no: 02.214 and 09.821], are no longer supported by Industry. Based on the available data, all 22 substances of this FGE are no longer of concern with respect to genotoxicity and can be evaluated through the Procedure.
Carcinogenicity_EU_PPP - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances which correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.033, 07.035, 07.094, 07.098, 07.112, 07.126, 07.129, 07.140, 7.146, 07.147, 07.172, 07.175, 07.196, 07.202 and 07.255] and eight are precursors for such ketones [FL-no: 02.062, 02.083, 02.101, 02.214, 09.143, 09.215, 09.821 and 09.870].
Carcinogenicity_EU_PPP - - - The European Food Safety Authority (EFSA) asked the Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. In the present revision of FGE.212, FGE.212Rev1, there has been a reassessment of [FL-no: 02.083, 02.101, 07.033, 07.035, 07.094, 07.098, 07.112, 07.129, 07.140, 07.172, 07.175, 07.196, 07.202 and 07.255] for which there were a request for genotoxicity data in FGE.212. Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances. The 23 substances correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones and eight are precursors for such ketones.
Carcinogenicity_EU_PPP - - - Following a request from the European commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.51, FGE.51Rev2, is due to new genotoxicity data evaluated in FGE.212Rev3 (EFSA CEF Panel, 2015a), which deals only with the genotoxic potential of alpha,beta-unsaturated flavouring substances. Based on these data, the Panel concluded that the data available could rule out the concern for genotoxicity for [FL-no: 07.033, 07.094, 07.112 and 07.140] and accordingly these substances can be evaluated through the Procedure in this revision.
Carcinogenicity_EU_PPP - - - The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. This revision is made due to inclusion of seven additional substances cleared for genotoxicity concern compared to the previous version. Furthermore, EU production volume on one substance and data on stereoisomerism for four substances have been provided since the publication of FGE.51. The present consideration concerns 20 alicyclic ketones, secondary alcohols and related esters evaluated by the JECFA at its 59th meeting and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of 17 secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols evaluated in the Flavouring Group Evaluation 09, Revision 3 (FGE.09Rev3).
Genetic Toxicity - - - Following a request from the European commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.51, FGE.51Rev2, is due to new genotoxicity data evaluated in FGE.212Rev3 (EFSA CEF Panel, 2015a), which deals only with the genotoxic potential of alpha,beta-unsaturated flavouring substances. Based on these data, the Panel concluded that the data available could rule out the concern for genotoxicity for [FL-no: 07.033, 07.094, 07.112 and 07.140] and accordingly these substances can be evaluated through the Procedure in this revision.
Genetic Toxicity - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advise for the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances which correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones [FL-no: 07.033, 07.035, 07.094, 07.098, 07.112, 07.126, 07.129, 07.140, 7.146, 07.147, 07.172, 07.175, 07.196, 07.202 and 07.255] and eight are precursors for such ketones [FL-no: 02.062, 02.083, 02.101, 02.214, 09.143, 09.215, 09.821 and 09.870].
Genetic Toxicity - - - Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212. Based on available genotoxicity data and new genotoxicity data submitted by the Industry, the Panel concluded that genotoxic potential could be ruled out for the six carvone derivatives [FL-no: 02.062, 07.146, 07.147, 09.143, 09.215 and 09.870], the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 in FGE.212, FGE.212Rev1 and FGE.212Rev3, respectively. Two substances previously included in FGE.212Rev2, vetiverol and vetiveryl acetate [FL-no: 02.214 and 09.821], are no longer supported by Industry. Based on the available data, all 22 substances of this FGE are no longer of concern with respect to genotoxicity and can be evaluated through the Procedure.
Genetic Toxicity - - - The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 24 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group Evaluation 212, Revision 2. The Panel concluded in FGE.212, that the genotoxic potential could be ruled out for d-carvone [FL-no: 07.146] together with the structurally related l-carvone [FL-no: 07.147] as well as carveol and the carvyl derivatives [FL-no: 02.062, 09.143, 09.215 and 09.870]. Based on available genotoxicity data and new submitted genotoxicity data from the Industry, the Panel concluded that the genotoxic potential could be ruled out for the 11 isophorone derivatives [FL-no: 02.083, 02.101, 07.035, 07.098, 07.126, 07.129, 07.172, 07.175, 07.196, 07.202 and 07.255] and the two vetiveryl derivatives [FL-no: 02.214 and 09.821] in FGE.212Rev1 and FGE.212Rev2, respectively. For the remaining five substances [FL-no: 07.033, 07.094, 07.112, 07.140 and 07.219] from subgroup 2.6 there is still a genotoxicity concern and additional data are required.
Genetic Toxicity - - - The European Food Safety Authority (EFSA) asked the Scientific Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was asked to evaluate flavouring substances using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. In the present revision of FGE.212, FGE.212Rev1, there has been a reassessment of [FL-no: 02.083, 02.101, 07.033, 07.035, 07.094, 07.098, 07.112, 07.129, 07.140, 07.172, 07.175, 07.196, 07.202 and 07.255] for which there were a request for genotoxicity data in FGE.212. Flavouring Group Evaluation 212 (FGE.212) concerns 23 substances. The 23 substances correspond to subgroup 2.6 of FGE.19. Fifteen of these substances are alpha,beta-unsaturated alicyclic ketones and eight are precursors for such ketones.
Genetic Toxicity - - - The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. This revision is made due to inclusion of seven additional substances cleared for genotoxicity concern compared to the previous version. Furthermore, EU production volume on one substance and data on stereoisomerism for four substances have been provided since the publication of FGE.51. The present consideration concerns 20 alicyclic ketones, secondary alcohols and related esters evaluated by the JECFA at its 59th meeting and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of 17 secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols evaluated in the Flavouring Group Evaluation 09, Revision 3 (FGE.09Rev3).

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE page FAQ dataset

What is the regulatory limit for 3-Methyl-5-propylcyclohex-2-en-1-one in cannabis?

3-Methyl-5-propylcyclohex-2-en-1-one does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for 3-Methyl-5-propylcyclohex-2-en-1-one?

3-Methyl-5-propylcyclohex-2-en-1-one does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for 3-Methyl-5-propylcyclohex-2-en-1-one?

3-Methyl-5-propylcyclohex-2-en-1-one has 6 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class II.

Is 3-Methyl-5-propylcyclohex-2-en-1-one also regulated in cosmetics or food?

3-Methyl-5-propylcyclohex-2-en-1-one has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.