EFSA toxicology reference values

Aspartame

SOURCE EFSA

Aspartame (CAS 22839-47-0). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.

Aspartame is a cannabis analyte contaminant represented in the cannabis public dataset.

CAS 22839-47-0 Cannabis Analyte

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE EFSA
Analyte name
Aspartame
CAS number
22839-47-0
Contaminant class
Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations
Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
22839-47-0

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE EFSA
Aspartame
CAS 22839-47-0 / mono-constituent substance
C14H18N2O5 / 6 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE EFSA
DescriptorValuePopulationEndpointBody
ADI 40 mg/kg bw/day consumers - other:
ADI 40 mg/kg bw/day consumers - other:
ADI 40 mg/kg bw/day consumers - other:
ADI 40 mg/kg bw/day consumers - other:
ADI 40 mg/kg bw/day consumers - other:

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE EFSA
EndpointSpeciesRouteEffectAssessment
Carcinogenicity_EU_PPP - - - In 2010, two articles have been published in the scientific literature, describing potential adverse health effects of sweeteners. The paper by Soffritti et al. (2010)4 reports that aspartame is a carcinogenic agent in mice. The publication by Halldorsson et al. (2010)5 suggests an association between consumption of artificially sweetened soft drinks and increased risk of preterm delivery. The ANS Panel will produce a Panel Statement on the two above mentioned scientific articles in order to advise EFSA on the need for further work.
Carcinogenicity_EU_PPP - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the results of a long-term carcinogenicity study with prenatal exposure to the artificial sweetener aspartame, performed by The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (ERF) and published in June 2007 by Soffritti et al.
Carcinogenicity_EU_PPP - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) of the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the re-evaluation of aspartame (E 951) as a food additive.
Carcinogenicity_EU_PPP - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the results of a long-term carcinogenicity study with prenatal exposure to the artificial sweetener aspartame, performed by The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (ERF) and published in June 2007 by Soffritti et al..
Carcinogenicity_EU_PPP - - - The European Food Safety Authority (EFSA) has been asked by the European Commission to assess the carcinogenicity study performed by the European Ramazzini Foundation of Oncology and Environmental Sciences (ERF) on the artificial sweetener aspartame, which was reported in publications in 2005 and 2006.
Carcinogenicity_EU_PPP - - - The European Food Safety Authority was asked to provide scientific advice on two studies, namely a carcinogenicity study in mice (Soffritti et al., 2010) and a prospective cohort study on the association between intakes of artificially sweetened soft drinks and preterm delivery (Halldorsson et al., 2010) and to conclude on the need to revise previous evaluations of aspartame or of the other sweeteners authorised in the European Union.
Genetic Toxicity - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) of the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the re-evaluation of aspartame (E 951) as a food additive.
Genetic Toxicity - - - The European Food Safety Authority was asked to provide scientific advice on two studies, namely a carcinogenicity study in mice (Soffritti et al., 2010) and a prospective cohort study on the association between intakes of artificially sweetened soft drinks and preterm delivery (Halldorsson et al., 2010) and to conclude on the need to revise previous evaluations of aspartame or of the other sweeteners authorised in the European Union.
Genetic Toxicity - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the results of a long-term carcinogenicity study with prenatal exposure to the artificial sweetener aspartame, performed by The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (ERF) and published in June 2007 by Soffritti et al.
Genetic Toxicity - - - The European Food Safety Authority (EFSA) has been asked by the European Commission to assess the carcinogenicity study performed by the European Ramazzini Foundation of Oncology and Environmental Sciences (ERF) on the artificial sweetener aspartame, which was reported in publications in 2005 and 2006.
Genetic Toxicity - - - Following a request from the European Commission, the Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to deliver a scientific opinion on the results of a long-term carcinogenicity study with prenatal exposure to the artificial sweetener aspartame, performed by The Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (ERF) and published in June 2007 by Soffritti et al..
Genetic Toxicity - - - In 2010, two articles have been published in the scientific literature, describing potential adverse health effects of sweeteners. The paper by Soffritti et al. (2010)4 reports that aspartame is a carcinogenic agent in mice. The publication by Halldorsson et al. (2010)5 suggests an association between consumption of artificially sweetened soft drinks and increased risk of preterm delivery. The ANS Panel will produce a Panel Statement on the two above mentioned scientific articles in order to advise EFSA on the need for further work.

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE Regulatory source

What is the regulatory limit for Aspartame in cannabis?

Aspartame does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for Aspartame?

Aspartame does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for Aspartame?

Aspartame has 5 EFSA OpenFoodTox reference value rows in the cannabis database, including ADI.

Is Aspartame also regulated in cosmetics or food?

Aspartame has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.